Natural and Synthetic Coumarins with Effects on Inflammation [PDF]
Molecules, 2016 In this review, we will present the different aspects of coumarins and derivatives, from natural origins or synthetically prepared, and their action on inflammation. Coumarins and also furo- and pyranocoumarins are found in many different plants.
Gilbert Kirsch +2 more
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Natural coumarins from Murraya paniculata as mixed-type inhibitors of cholinesterases: In vitro and in silico investigations [PDF]
Frontiers in Pharmacology, 2023 Currently, acetylcholinesterase (AChE) inhibiting drugs in clinical use, such as tacrine, donepezil, rivastigmine, and galanthamine, are associated with serious side effects and short half-lives.
Asaad Khalid +15 more
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Natural coumarins: Preclinical evidence-based potential candidates to alleviate diabetic nephropathy
Phytomedicine Plus, 2022 Background: Cis-o-hydroxycinnamic acid lactones, referred to as natural coumarin, have a basic skeleton of benzopyranone in their structure. The natural coumarins are typically found abundantly in roots, rhizomes, bark, and leaves of the plant belonging ...
Sitara Ghosh +6 more
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Coumarins in the tumor-immune application: from molecular mechanisms to therapeutic innovations [PDF]
Frontiers in ImmunologyCoumarin compounds represent a class of natural or synthetic molecules characterized by a benzo-α-pyrone skeleton. Their diverse substituents and extensive biological activities have garnered significant attention in the fields of anti-tumor therapy and ...
Yufan Zhao +4 more
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Coumarins: Quorum Sensing and Biofilm Formation Inhibition
MoleculesQuorum sensing (QS) is a bacterial cell-to-cell communication mechanism that plays an essential role in bacterial pathogenesis. QS governs bacterial behavior and controls biofilm formation, which in turn contributes to antibiotic resistance.
Eslam R. El-Sawy +3 more
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Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials [PDF]
المجلة العراقية للصيدلة, 2022 Background: Natural coumarins group, a principal member of the benzopyrone family, is one of the naturally occurring substances obtained ordinarily from plant origins, with antibacterial, anticoagulant, antihypertensive, anticancer, antioxidant, anti ...
Rahma Jebir, Yasser Mustafa
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Coumarin-based products: Their biodiversity and pharmacology [PDF]
المجلة العراقية للصيدلة, 2022 Background: The plant kingdom generates and releases a wide range of secondary-metabolites, which have several effects on biological, toxicological, and ecological systems that may act in a similar manner to chemically synthesized compounds. One of these
Reem Ismael +2 more
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Safety Profile of Nutraceuticals Rich in Coumarins: An Update
Frontiers in Pharmacology, 2022 Coumarins are a family of benzopyrones largely distributed in the natural kingdom, being present in the seeds, fruits, flowers, or roots of various plant species.
Simona Codruta Heghes +6 more
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Coumarins as Fungal Metabolites with Potential Medicinal Properties
Antibiotics, 2022 Coumarins are a structurally varied set of 2H-chromen-2-one compounds categorized also as members of the benzopyrone group of secondary metabolites. Coumarin derivatives attract interest owing to their wide practical application and the unique reactivity
Olga M. Tsivileva +2 more
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Effects of Structural Manipulation on the Bioactivity of some Coumarin-Based Products [PDF]
Archives of Razi Institute, 2021 Coumarin (2H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties, such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral, anticancer, antihypertensive, antitubercular, anticonvulsant ...
Y Fakri Mustafa +4 more
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