2-Oxoglutarate-dependent dioxygenases in the biosynthesis of simple coumarins [PDF]
Frontiers in Plant Science, 2014 Coumarins are natural plant products that have been the subject of extensive phytochemical and pharmacological research studies in the past few decades.
Bun-Ichi eShimizu
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Rhizobacteria opportunistically boost colonization and impair plant fitness by degrading plant-derived coumarins under iron deficiency [PDF]
Nature CommunicationsPlants recruit root-associated bacterial assemblies primarily through the secretion of specialized metabolites, and the resultant rhizospheric microbiota is empirically considered beneficial.
Yichao Gu +3 more
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Growth Year and Chemotype Synergistically Regulate Coumarin Accumulation and the Associated Transcriptional Profiles in Peucedanum praeruptorum Dunn [PDF]
PlantsPeucedanum praeruptorum is increasingly cultivated as wild resources are depleted. However, cultivated plants often contain lower levels of coumarins than wild individuals and may not meet the standards of the Chinese Pharmacopoeia.
Jiemei Jiang +9 more
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Knoevenagel Reaction in [MMIm][MSO4]: Synthesis of Coumarins
Molecules, 2011 The ionic liquid 1,3-dimethylimidazolium methyl sulfate, [MMIm][MSO4], together with a small amount of water (the amount taken up by the ionic liquid upon exposure to air), acts efficiently as both solvent and catalyst of the Knoevenagel condensation ...
Emilia Tojo +2 more
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Combining metabolomics and transcriptomics to reveal the effect of β-glucosidase on scopolin in Angelica dahurica var. formosana [PDF]
BMC Plant BiologyAngelica dahurica var. formosana (ADF), a diversified variety that integrates medicine, food, and cosmetics, possessing abundant coumarin compounds. One of the pharmacologically active and aromatic components found in it is coumarins.
Yalan Wang +7 more
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Advancing the Potential of Ostericum palustre (Besser) Besser (Synonym Angelica pancicii Vandas ex. Velen.) of Bulgarian Origin as a Source of Bioactive Compounds: Metabolite Profiling and Pharmacological Activity [PDF]
PlantsOstericum palustre (Besser) Besser (synonym Angelica pancicii Vandas ex. Velen.) is a Eurasian species from the Apiaceae family, previously related to the Balkan endemic species A. pancicii.
Reneta Gevrenova +5 more
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Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials [PDF]
المجلة العراقية للصيدلة, 2022 Background: Natural coumarins group, a principal member of the benzopyrone family, is one of the naturally occurring substances obtained ordinarily from plant origins, with antibacterial, anticoagulant, antihypertensive, anticancer, antioxidant, anti ...
Rahma Jebir, Yasser Mustafa
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Molecules, 2021 Coumarins are phytochemicals occurring in the plant kingdom, which biosynthesis is induced under various stress factors. They belong to the wide class of specialized metabolites well known for their beneficial properties.
Izabela Perkowska +7 more
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Detection of coumarin derivatives of Viola odorata cultivated in Iraq
Journal of Pharmacy and Bioallied Sciences, 2023 Like other members of the viola family, Viola odorata may be found naturally occurring in Europe and Asia. This little plant is tough and perennially herbaceous. It's also known as sweet violet and English violet.
Zainab Aziz Ali +2 more
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Coumarins inhibit η-class carbonic anhydrase from Plasmodium falciparum
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Coumarins were discovered to act as inhibitors of α-carbonic anhydrases (CAs, EC 4.2.1.1) after undergoing hydrolysis mediated by the esterase activity of the enzyme to the corresponding 2-hydroxycinnamic acids.
Simone Giovannuzzi +4 more
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