Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins
4-Methyl-8-formyl- and 4-phenyl-8-formyl coumarins have been synthesized by Pechmann reaction using oxalic acid catalyst for the first time. 4-Propyl-7-hydroxy-, and 4-methyl-7-methoxy coumarins have also been accomplished by this catalyst for the first ...
H. Ç. Onar, B. A.Vardar
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Natural coumarins: Preclinical evidence-based potential candidates to alleviate diabetic nephropathy
Background: Cis-o-hydroxycinnamic acid lactones, referred to as natural coumarin, have a basic skeleton of benzopyranone in their structure. The natural coumarins are typically found abundantly in roots, rhizomes, bark, and leaves of the plant belonging ...
Sitara Ghosh +6 more
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COSY catalyses trans-cis isomerization and lactonization in the biosynthesis of coumarins [PDF]
Coumarins, also known as 1,2-benzopyrones, comprise a large class of secondary metabolites that are ubiquitously found throughout the plant kingdom.
Boerjan, Wout +15 more
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2-Oxoglutarate-dependent dioxygenases in the biosynthesis of simple coumarins
Coumarins are natural plant products that have been the subject of extensive phytochemical and pharmacological research studies in the past few decades.
Bun-Ichi eShimizu
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3-Substituted Coumarins Inhibit NorA and MepA Efflux Pumps of Staphylococcus aureus
Coumarins are compounds with scientifically proven antibacterial properties, and modifications to the chemical structure are known to improve their effects.
José B. de Araújo-Neto +14 more
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Coumarins, naturally occurring phytochemicals, display a wide spectrum of biological activities by acting on multiple targets. Herein, nine coumarins from the root of Toddalia asiatica were evaluated for activities related to pathogenesis of Alzheimer’s ...
Pitchayakarn Takomthong +7 more
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HYDROGEN-BONDED SUPRAMOLECULAR ARRAY IN THE CRYSTAL STRUCTURE OF ETHYL 7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLATE MONOHYDRATE [PDF]
Indexación: Web of Science; ScieloThe crystal structure of ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate monohydrate (1), C12H10O5.H2O, was established by X-ray crystallographic analysis.
CASSELS, BRUCE K. +2 more
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Safety Profile of Nutraceuticals Rich in Coumarins: An Update
Coumarins are a family of benzopyrones largely distributed in the natural kingdom, being present in the seeds, fruits, flowers, or roots of various plant species.
Simona Codruta Heghes +6 more
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Auraptene Promotes THP-1 Polarization to M1 Macrophages and Improves M1 Function [PDF]
Background and Objectives: Macrophages play an important role in tumor growth (M2 macrophage) or suppression (M1 macrophage). Auraptene, a prenyloxycoumarin compound extracted from Citrus plants, has anti-cancer and anti-inflammatory properties.
Afshin Jalali +3 more
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Secondary metabolites with ecologic and medicinal implications in Anthemis cretica subsp. petraea from Majella National Park [PDF]
Anthemis cretica subsp. petraea (Ten.) Greuter is a plant belonging to the Asteraceae family and endemic of central Italy. In this paper, the first analysisof the ethanolic fraction of samples collected in the Majella National Park is reported.
Alessandro Venditti +7 more
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