Results 11 to 20 of about 71,972 (342)

Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins

open access: diamondBulletin of the Chemical Society of Ethiopia, 2018
4-Methyl-8-formyl- and 4-phenyl-8-formyl coumarins have been synthesized by Pechmann reaction using oxalic acid catalyst for the first time. 4-Propyl-7-hydroxy-, and 4-methyl-7-methoxy coumarins have also been accomplished by this catalyst for the first ...
H. Ç. Onar, B. A.Vardar
doaj   +3 more sources

Natural coumarins: Preclinical evidence-based potential candidates to alleviate diabetic nephropathy

open access: yesPhytomedicine Plus, 2022
Background: Cis-o-hydroxycinnamic acid lactones, referred to as natural coumarin, have a basic skeleton of benzopyranone in their structure. The natural coumarins are typically found abundantly in roots, rhizomes, bark, and leaves of the plant belonging ...
Sitara Ghosh   +6 more
doaj   +1 more source

COSY catalyses trans-cis isomerization and lactonization in the biosynthesis of coumarins [PDF]

open access: yes, 2019
Coumarins, also known as 1,2-benzopyrones, comprise a large class of secondary metabolites that are ubiquitously found throughout the plant kingdom.
Boerjan, Wout   +15 more
core   +1 more source

2-Oxoglutarate-dependent dioxygenases in the biosynthesis of simple coumarins

open access: yesFrontiers in Plant Science, 2014
Coumarins are natural plant products that have been the subject of extensive phytochemical and pharmacological research studies in the past few decades.
Bun-Ichi eShimizu
doaj   +1 more source

3-Substituted Coumarins Inhibit NorA and MepA Efflux Pumps of Staphylococcus aureus

open access: yesAntibiotics, 2023
Coumarins are compounds with scientifically proven antibacterial properties, and modifications to the chemical structure are known to improve their effects.
José B. de Araújo-Neto   +14 more
doaj   +1 more source

Structure–Activity Analysis and Molecular Docking Studies of Coumarins from Toddalia asiatica as Multifunctional Agents for Alzheimer’s Disease

open access: yesBiomedicines, 2020
Coumarins, naturally occurring phytochemicals, display a wide spectrum of biological activities by acting on multiple targets. Herein, nine coumarins from the root of Toddalia asiatica were evaluated for activities related to pathogenesis of Alzheimer’s ...
Pitchayakarn Takomthong   +7 more
doaj   +1 more source

HYDROGEN-BONDED SUPRAMOLECULAR ARRAY IN THE CRYSTAL STRUCTURE OF ETHYL 7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLATE MONOHYDRATE [PDF]

open access: yes, 2010
Indexación: Web of Science; ScieloThe crystal structure of ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate monohydrate (1), C12H10O5.H2O, was established by X-ray crystallographic analysis.
CASSELS, BRUCE K.   +2 more
core   +2 more sources

Safety Profile of Nutraceuticals Rich in Coumarins: An Update

open access: yesFrontiers in Pharmacology, 2022
Coumarins are a family of benzopyrones largely distributed in the natural kingdom, being present in the seeds, fruits, flowers, or roots of various plant species.
Simona Codruta Heghes   +6 more
doaj   +1 more source

Auraptene Promotes THP-1 Polarization to M1 Macrophages and Improves M1 Function [PDF]

open access: yesResearch Journal of Pharmacognosy, 2022
Background and Objectives: Macrophages play an important role in tumor growth (M2 macrophage) or suppression (M1 macrophage). Auraptene, a prenyloxycoumarin compound extracted from Citrus plants, has anti-cancer and anti-inflammatory properties.
Afshin Jalali   +3 more
doaj   +1 more source

Secondary metabolites with ecologic and medicinal implications in Anthemis cretica subsp. petraea from Majella National Park [PDF]

open access: yes, 2016
Anthemis cretica subsp. petraea (Ten.) Greuter is a plant belonging to the Asteraceae family and endemic of central Italy. In this paper, the first analysisof the ethanolic fraction of samples collected in the Majella National Park is reported.
Alessandro Venditti   +7 more
core   +2 more sources

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