Results 11 to 20 of about 25,230 (162)
Detection of coumarin derivatives of Viola odorata cultivated in Iraq
Journal of Pharmacy and Bioallied Sciences, 2023 Like other members of the viola family, Viola odorata may be found naturally occurring in Europe and Asia. This little plant is tough and perennially herbaceous. It's also known as sweet violet and English violet.
Zainab Aziz Ali +2 more
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A Review on Anti-Tumor Mechanisms of Coumarins
Frontiers in Oncology, 2020 Coumarins are a class of compound with benzopyrone as their basic structure. Due to abundant sources, easy synthesis, and various pharmacological activities, coumarins have attracted extensive attention from researchers.
Yi Wu +4 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Different 2,4-thiazolidinedione-tethered coumarins 5a–b, 10a–n and 11a–d were synthesised and evaluated for their inhibitory action against the cancer-associated hCAs IX and XII, as well as the physiologically dominant hCAs I and II to explore their ...
Wagdy M. Eldehna +12 more
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Natural coumarins: Preclinical evidence-based potential candidates to alleviate diabetic nephropathy
Phytomedicine Plus, 2022 Background: Cis-o-hydroxycinnamic acid lactones, referred to as natural coumarin, have a basic skeleton of benzopyranone in their structure. The natural coumarins are typically found abundantly in roots, rhizomes, bark, and leaves of the plant belonging ...
Sitara Ghosh +6 more
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2-Oxoglutarate-dependent dioxygenases in the biosynthesis of simple coumarins
Frontiers in Plant Science, 2014 Coumarins are natural plant products that have been the subject of extensive phytochemical and pharmacological research studies in the past few decades.
Bun-Ichi eShimizu
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Biomedicines, 2020 Coumarins, naturally occurring phytochemicals, display a wide spectrum of biological activities by acting on multiple targets. Herein, nine coumarins from the root of Toddalia asiatica were evaluated for activities related to pathogenesis of Alzheimer’s ...
Pitchayakarn Takomthong +7 more
doaj +1 more source
3-Substituted Coumarins Inhibit NorA and MepA Efflux Pumps of Staphylococcus aureus
Antibiotics, 2023 Coumarins are compounds with scientifically proven antibacterial properties, and modifications to the chemical structure are known to improve their effects.
José B. de Araújo-Neto +14 more
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Antagonists of Vitamin K—Popular Coumarin Drugs and New Synthetic and Natural Coumarin Derivatives
Molecules, 2020 Many natural coumarins and their chemically synthesized analogs and derivatives exert diverse properties, such as anticancer, antioxidant, anti-inflammatory, or anticoagulant, with the latter being of the utmost importance.
Kinga Kasperkiewicz +4 more
doaj +1 more source
Safety Profile of Nutraceuticals Rich in Coumarins: An Update
Frontiers in Pharmacology, 2022 Coumarins are a family of benzopyrones largely distributed in the natural kingdom, being present in the seeds, fruits, flowers, or roots of various plant species.
Simona Codruta Heghes +6 more
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Auraptene Promotes THP-1 Polarization to M1 Macrophages and Improves M1 Function [PDF]
Research Journal of Pharmacognosy, 2022 Background and Objectives: Macrophages play an important role in tumor growth (M2 macrophage) or suppression (M1 macrophage). Auraptene, a prenyloxycoumarin compound extracted from Citrus plants, has anti-cancer and anti-inflammatory properties.
Afshin Jalali +3 more
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