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BENZOPYRAN: A BIOLOGICALLY ACTIVE SCAFFOLD

open access: yesInternational Journal of Biology, Pharmacy and Allied Sciences
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New benzopyrans: Anticonvulsant activities

Life Sciences, 1975
Three new analogs of dimethylheptylpyran (DMHP) (SP-141, SP-143, and SP-175) were found to exhibit significant anticonvulsant activity against audiogenic, supramaximal electroshock, and maximal pentylentetrazol induced seizures in mice. In rats, all three compounds were found to be more active than diphenylhydantoin in the supramaximal electroshock ...
N P, Plotnikoff   +4 more
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Benzopyrans from Hypericum polyanthemum

Phytochemistry, 2001
From the aerial parts of Hypericum polyanthemum Klotzsch ex Reichardt (Guttiferae), three chromenes, 6-isobutyryl-5,7-dimethoxy-2,2-dimethyl-benzopyran; 7-hydroxy-6-isobutyryl-5-methoxy-2,2-dimethyl-benzopyran and 5-hydroxy-6-isobutyryl-7-methoxy-2,2-dimethyl-benzopyran were isolated. Their structures were determined by NMR spectroscopic analyses.
A B, Ferraz   +4 more
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Benzopyran derivatives from Mallotus apelta

Phytochemistry, 2001
From the leaves of Mallotus apelta, seven benzopyran compounds were obtained and their structures were determined using spectroscopic methods. One showed moderate antibiotic activity against Micrococcus lutens.
T Y, An, L H, Hu, X F, Cheng, Z L, Chen
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