Results 61 to 70 of about 10,026 (250)
A study of the solid-state intermolecular interactions of twenty-nine benzopyrans substituted with polyhaloalkyl groups was carried out by quantum chemical calculations using the Mercury and WinGX computer programs.
Lissette A. Haro-Saltos +2 more
doaj +1 more source
Sharpless asymmetric dihydroxylation of styrene derivative 6 afforded chiral triols (R)-7 and (S)-7, which were cyclized with tosyl chloride in the presence of Bu2SnO to provide 2-benzopyrans (R)-4 and (S)-4 with high regioselectivity.
Katharina Holl +8 more
doaj +1 more source
Eryngium heterophyllum has 85 metabolites according to nontargeted UHPLC‐QTOF‐MS profiling, with flavonoids and phenylpropionic acids emerging as significantly related bioactive families. In silico compound–disease–target networks connect 31 metabolites to inflammation, diabetes, obesity, and cardiovascular disease associated with metabolic syndrome ...
Citlaly Gutiérrez‐Rodelo +5 more
wiley +1 more source
Photochemical studies on 3,4-epoxy-3,4-dihydro-2H-1-benzopyrans
Photochemical behaviour of 3,4-epoxy-3,4-dihydro-2H-1-benzopyrans, intermediates in the synthesis of pterocarpans, has been studied in various solvents.
Balasubramanian, K. K. +2 more
core +1 more source
Insertion of monosubstituted allenes into stable oxapalladacycle I was studied. The aim of this work was to define steric and electronic parameters of allenes that would allow for a regio- and diastereoselective synthesis of 2,3-disubstituted 3,4-dihydro-
Helena C. Malinakova (1915663) +1 more
core +2 more sources
ABSTRACT Poly(ADP‐ribose) polymerase‐1 (PARP‐1) plays a central role in the repair of DNA single‐strand breaks and represents an established therapeutic target in cancer treatment. In this study, a series of novel oxadiazole–morpholine hybrid compounds was designed and synthesized using a structure‐based drug design approach to target the catalytic ...
Nader R. Albujuq +6 more
wiley +1 more source
Approximately 400 Garcinia species are distributed around the world. Previous studies have reported the extracts from bark, seed, fruits, peels, leaves, and stems of Garcinia mangostana, G. xanthochymus, and G.
Ting-Hsu Chen +3 more
doaj +1 more source
ABSTRACT Aim Tegoprazan, a potassium‐competitive acid blocker, is an acid‐suppressing medication under review as a potential alternative treatment in cases of erosive esophagitis. This systematic review and meta‐analysis assesses the efficacy and tolerability of tegoprazan compared to proton pump inhibitors, the current standard of care. Methods Pubmed,
Youssef Diab +6 more
wiley +1 more source
The tendency for alkaloid–flavonoid cocrystal formation is found to be markedly different for theophylline (Tph) compared to its 8‐halo analogues. Through screening with 13 common flavonoids, Tph is found to form cocrystals with six flavonoids, whereas 8‐Cl‐Tph and 8‐Br‐Tph each form cocrystals with just two, myricetin and kaempferol.
Weijian Ye +2 more
wiley +1 more source
Synthesis of Benzopyran Atropisomers via Electrophilic Halogenation
We report a halogenation‐based method for the synthesis of axially chiral benzopyrans, tolerating diverse substituents and halogens (Br, Cl, and I). A double bromination gives bisbenzopyrans with two stereogenic axes. Preliminary enantioselective conditions yield benzopyran atropisomer with up to 56% ee.
Alix Bourhis +3 more
wiley +1 more source

