Results 71 to 80 of about 3,681 (218)
Identification of distant drug off-targets by direct superposition of binding pocket surfaces. [PDF]
, 2013 Correctly predicting off-targets for a given molecular structure, which would have the ability to bind a large range of ligands, is both particularly difficult and important if they share no significant sequence or fold similarity with the respective ...
Armen, Roger S, Schumann, Marcel
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MedComm, Volume 7, Issue 4, April 2026.This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva +3 more
wiley +1 more source
Chemistry ProceedingsA study of the solid-state intermolecular interactions of twenty-nine benzopyrans substituted with polyhaloalkyl groups was carried out by quantum chemical calculations using the Mercury and WinGX computer programs.
Lissette A. Haro-Saltos +2 more
doaj +1 more source
Pharmaceuticals, 2014 Sharpless asymmetric dihydroxylation of styrene derivative 6 afforded chiral triols (R)-7 and (S)-7, which were cyclized with tosyl chloride in the presence of Bu2SnO to provide 2-benzopyrans (R)-4 and (S)-4 with high regioselectivity.
Katharina Holl +8 more
doaj +1 more source
Cell Signaling Underlying Epileptic Behavior [PDF]
, 2011 Epilepsy is a complex disease, characterized by the repeated occurrence of bursts of electrical activity (seizures) in specific brain areas. The behavioral outcome of seizure events strongly depends on the brain regions that are affected by overactivity.
Yuri eBozzi +4 more
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Graphene Oxide-Supported Oxime Palladacycles as Efficient Catalysts for the Suzuki–Miyaura Cross-Coupling Reaction of Aryl Bromides at Room Temperature under Aqueous Conditions [PDF]
, 2017 Palladacycles are highly efficient precatalysts in cross-coupling reactions whose immobilization on carbonaceous materials has been hardly studied.
Alonso, Diego A. +2 more
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Biomolecules, 2019 Approximately 400 Garcinia species are distributed around the world. Previous studies have reported the extracts from bark, seed, fruits, peels, leaves, and stems of Garcinia mangostana, G. xanthochymus, and G.
Ting-Hsu Chen +3 more
doaj +1 more source
Archiv der Pharmazie, Volume 359, Issue 3, March 2026.Chromone‐based derivatives were synthesized and evaluated for selective inhibition of tumor‐associated carbonic anhydrases IX and XII. Structure–activity relationships, docking studies, and ADMET profiling revealed promising candidates with selective tumoral isoform inhibition, supporting their potential as anticancer leads. ABSTRACT A small library of
Lisa Sequeira +13 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.ABSTRACT Propolis is a polyphenol‐rich natural resin with well‐documented antioxidant activity; however, its practical application is restricted by poor aqueous solubility and limited stability. Herein, propolis‐based organic–inorganic hybrid nanoflowers (Prp‐Nfs) were synthesized by integrating a propolis extract into a Cu3(PO4)2·3H2O matrix under ...
Cevahir Altinkaynak, Fatih Kirmizikar
wiley +1 more source
Phytochemicals and Anti-Inflammatory Activity of Melicope Ptelefolia Champ Ex Benth [PDF]
, 2005 Leaves of Melicope ptelefolia Champ ex Benth were examined for phytochemicals. Using various chromatography techniques such as normal column chromatography, gel filtration on sephadex LH-20 and radial chromatography seven compounds were isolated ...
Suryati,
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