Results 21 to 30 of about 9,160 (182)

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

open access: yesAngewandte Chemie, EarlyView.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +2 more sources

The choice of method of introduction of active substances into the basis of the cream for the treatment of acne and demodecosis

open access: yesФармацевтичний журнал, 2021
Among dermatological diseases demodicosis and acne occupy a very important place. The incidence of demodicosis is more than 5% and ranks seventh in frequency among dermatological diseases. It is known that demodicosis can turn into acne.
A. S. Koval
doaj   +1 more source

Use of Cyclic Di- and Triperoxides as Initiators of Styrene Polymerization at High Temperature with a View to Their Use in Industrial Applications

open access: yesMolecules, 2000
In industry, the bulk free radical polymerization of styrene takes place with the aid of peroxide initiators such as benzoyl peroxide. In this work di- and trimeric cyclic peroxides were used as initiators of the styrene polymerization in order to ...
A. I. Cañizo   +3 more
doaj   +1 more source

Individual sol-gel microencapsulation of benzoyl peroxide and tretinoin enables controlled release onto the skin

open access: yesHeliyon
A combination of benzoyl peroxide (BPO) and tretinoin is recommended for treating acne; however, concurrent administration can be irritating, and coformulation is prevented by BPO-mediated oxidation of tretinoin.
Hila Hakak   +3 more
doaj   +1 more source

Experience with the fixed combination of benzoyl peroxide and clindamycin in acne therapy [PDF]

open access: yesVestnik Dermatologii i Venerologii
Background. Acne is one of the most common dermatoses, affecting more than 9% of the world’s population. Acne negatively affects the patient’s quality of life and self-esteem, often leading to the development of anxiety and depression. The combination of
Anna A. Verchoumova   +2 more
doaj   +1 more source

Chemical constituents from methanolic extract of Solanum procumbens Lour (Solanaceae)

open access: yesVietnam Journal of Science, Technology and Engineering, 2022
Solanum procumbens L. (Solanaceae) were extracted respectively with n-hexane, ethyl acetate, and methanol to obtain the corresponding extracts. The methanolsoluble extract was acidified by adding HCl 0.5 M; this was followed by liquid-liquid partition ...
Thi Thanh Thuy Tran   +2 more
doaj   +1 more source

Comparative evaluation of therapy results in mild acne

open access: yesМедицинский совет, 2022
Introduction. Mild acne is the most underestimated form of the disease.The aim of the study was to compare the results of external combination therapy with 15% azelaic acid gel + 1% clindamycin gel and benzoyl peroxide + clindamycin for mild ...
I. M. Khismatulina   +3 more
doaj   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

open access: yesAdvanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou   +17 more
wiley   +1 more source

Synthesis of Renewable Poly(limonene): A Kinetic Modeling Study to Improve the Polymerization [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2020
Despite its potential in the production of polymers from renewable sources, D-limonene faces difficulties in its polymerization, resulting in low monomer conversion and molar mass.
Felipe Mourão Coelho   +1 more
doaj   +2 more sources

Spatial Control Over Tether‐Tunable Coordination on Palladium for Divergent Synthesis of Bicyclo[n.1.0]alkanes via Oxidative Cyclopropanation of Enynes

open access: yesAdvanced Science, EarlyView.
We have developed a Pd‐catalyzed oxidative cyclopropanation of 1,n‐enynes employing cyclic diacyl peroxides as bifunctional reagents that serve as both tether‐tunable oxidants and spatially controlled dicarboxylate anions. ABSTRACT Bicyclo[n.1.0]alkanes are highly valuable scaffolds in drug discovery and synthetic chemistry.
Ting Yuan, Lei Shi
wiley   +1 more source

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