Organocatalytic stereodivergent synthesis of β,β-disubstituted-α-aminoacids [PDF]
In this work, we present an organocatalytic stereodivergent synthesis of β,β-disubstituted-α-aminoacids using arylidene azlactones as starting materials.
Martinelli, Ada
core
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun +14 more
wiley +1 more source
Iron(III) chelating resins-IV. Crosslinked copolymer beads of 1-(B-acrylamidoethyl)-3-hydroxy-2-methyl-4(1H)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA) [PDF]
Iron(III) chelating beads have been synthesized by copolymerization of 1-(ß-acrylamidoethyl)-3-hydroxy-2-methyl-4(IH)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA), and ethyleneglycol dimethacrylate (EGDMA) as the crosslinking agent.
Bantjes, A. +2 more
core +3 more sources
Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source
Selective oxidation of benzyl alcohol to benzaldehyde over Ce-modified algal-based biochar
As an important chemical intermediate, benzaldehyde is widely used in medicine and fine chemicals. To address pollution in traditional benzaldehyde synthesis, preparing benzaldehyde through the catalytic oxidation of benzyl alcohol holds significant ...
Ying HE +5 more
doaj +1 more source
Coupling of 1-alkyl-2-(bromomethyl)aziridines with heteroatom-centered nucleophiles towards 2-[(heteroatom)methyl]aziridines [PDF]
The reactivity of 1-alkyl-2-(bromomethyl)aziridines with respect to different types of oxygen-, nitrogen- and sulphur-centered nucleophiles has been evaluated, pointing to the conclusion that these substrates can be applied successfully as synthetic ...
D'hooghe, Matthias, De Kimpe, Norbert
core +2 more sources
Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards +8 more
wiley +1 more source
Recent Advances in Mediator and Proton Relay Usage in Molecular Catalysis
The use of electron–proton transfer mediators, redox mediators, and proton relays in synergy with molecular catalysts in energy‐related small‐molecule and organic transformations is discussed, with a focus on recent advances. Linear free‐energy relationship and catalytic Tafel plots provide a systematic foundation for benchmarking these catalytic ...
Yu‐Lin Chi +3 more
wiley +1 more source
Opto-fluidic third order distributed feed-back dye laser [PDF]
This letter describes the design and operation of a polymer-based third order distributed feed-back (DFB) microfluidic dye laser. The device relies on light-confinement in a nano-structured polymer film where an array of nanofluidic channels is filled by
Gersborg-Hansen, Morten +1 more
core +2 more sources
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang +9 more
wiley +1 more source

