Results 81 to 90 of about 8,048 (168)

Defective apoptosis of U937 cells induced by benzyl isothiocyanate (BITC)

Acta Biochimica Polonica, 2019
Isothiocyanates’ precursors (ITCs), including benzyl isothiocyanate (BITC), are considered as cancer chemopreventive agents. ITC derivatives were tested in clinical trials (NCT00005883, NCT01265953, NCT01790204) and preclinical studies aimed to inhibit tumor growth and modulation of their microenvironment.
Grzegorz Stasiłojć, Anna Nagel, Patrycja Koszałka, Jacek Jerzy Bigda   +3 more
openaire   +3 more sources

Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation therapy

Frontiers in Bioscience, 2009
Increase in systemic toxicity and resistance are the major drawbacks of radiation therapy in the treatment of pancreatic cancer. We have shown previously that BITC inhibits the growth of human pancreatic cancer cells and induces apoptosis. Here we determined whether BITC could sensitize BxPC-3 cells and increase the therapeutic potential of gamma ...
Ravi Prakash, Sahu, Michael Wayne, Epperly, Sanjay Kumar, Srivastava   +2 more
openaire   +2 more sources

Determinação de isotiocianato de benzila em Carica papaya utilizando cromatografia gasosa com detectores seletivos Determination of benzyl isothiocyanate in Carica papaya using gas chromatography with selectives detectors

Química Nova, 2008
In the present work, a method was developed and validated for the quantification of benzyl isothiocyanate (BITC) in the fruits of Carica papaya. The quantification of this compound was carried out by gas chromatography (GC) with selective detectors ...
Izabela Miranda de Castro, Marianna Ramos dos Anjos, Elba dos Santos de Oliveira   +2 more
doaj   +1 more source

Isothiocyanates: An Overview of Their Antimicrobial Activity against Human Infections

Molecules, 2018
The use of plant-derived products as antimicrobial agents has been investigated in depth. Isothiocyanates (ITCs) are bioactive products resulting from enzymatic hydrolysis of glucosinolates (GLs), the most abundant secondary metabolites in the botanical ...
Letizia Romeo, Renato Iori, Patrick Rollin, Placido Bramanti, Emanuela Mazzon   +4 more
doaj   +1 more source

Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers

Molecules, 2018
Glucosinolates (GSL) are naturally occurring β-d-thioglucosides found across the cruciferous vegetables. Core structure formation and side-chain modifications lead to the synthesis of more than 200 types of GSLs in Brassicaceae.
Prabhakaran Soundararajan, Jung Sun Kim
doaj   +1 more source

Molecular Targets of Benzyl Isothiocyanates in Pancreatic Cancer

, 2012
Addiction of cancer cells to survival pathways has been well documented in most of the cancer models including the pancreatic cancer. Pancreatic cancer is one of the most aggressive tumors with an average five year survival rate of less than 5% (Jemal A et al., 2010).
Boreddy, Srinivas Reddy, Pramanik, Kartick C., Srivastava, Sanjay K.   +2 more
openaire   +3 more sources

Benzyl Cyanide, Benzyl Thiocyanate and Benzyl Isothiocyanate, Gas Chromatographic Data and Determination. [PDF]

Acta Chemica Scandinavica, 1964
Ö Wahlroos, Maija Saarivirta, Kazimierz Toczko, D. R. Sparrow   +3 more
openaire   +1 more source

Preparation and characterization of 3D-printed antibacterial hydrogel with benzyl isothiocyanate. [PDF]

Int J Bioprint, 2023
Liang Y, Chitrakar B, Liu Z, Ming X, Xu D, Mo H, Shi C, Zhu X, Hu L, Li H.   +9 more
europepmc   +1 more source

Methoxy-substituted Benzyl Isothiocyanates and N-Benzylthioureas. [PDF]

Acta Chemica Scandinavica, 1971
Erik Bach, Anders Kjær, B. J. Welch, A. Prelesnik, I. Zupancic, L. Ehrenberg   +5 more
openaire   +1 more source

[Corrigendum] Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β‑catenin pathway. [PDF]

Mol Med Rep, 2022
Xie B, Zhao L, Guo L, Liu H, Fu S, Fan W, Lin L, Chen J, Wang B, Fan L, Wei H.   +10 more
europepmc   +1 more source