Results 81 to 90 of about 8,965 (194)

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

open access: yesPhytotherapy Research, Volume 40, Issue 6, Page 3250-3266, June 2026.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta   +7 more
wiley   +1 more source

ANTIMICROBIAL ISOTHIOCYANATE DERIVATIVES FROM SALVADORA PERSICA ROOT "SIWAK" EXTRACT

open access: yes, 2017
Phytochemical study directed by antimicrobial activity testing of the root extract of Salvadora persica known as “Siwak” was conducted to identify the antimicrobial components.
Maged S. Abdel-Kader 1,2 , Magdi M. Muharram 1,3, Ahmed I. Foudah1 , Mohammed H. Alqarni1 , Mohammed A. Salkini 1
core   +1 more source

Antimicrobial Activity and Chromatographic Analysis of Extracts from Tropaeolum pentaphyllum Lam. Tubers

open access: yesMolecules, 2016
Background: Tropaeolum pentaphyllum Lam. tubers (Tropaeolaceae) are known and used as a condiment and for the treatment of skin infections in Southern Brazil. However, its activity and composition has not yet been investigated.
Ritiel Corrêa da Cruz   +5 more
doaj   +1 more source

Yeast screening system reveals the inhibitory mechanism of cancer cell proliferation by benzyl isothiocyanate through down-regulation of Mis12. [PDF]

open access: yesSci Rep, 2019
Benzyl isothiocyanate (BITC) is a naturally-occurring isothiocyanate derived from cruciferous vegetables. BITC has been reported to inhibit the proliferation of various cancer cells, which is believed to be important for the inhibition of tumorigenesis ...
Abe-Kanoh N   +8 more
europepmc   +2 more sources

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Benzyl Isothiocyanate Induces Growth Inhibition and Cell Apoptosis in Human Melanoma A375.S2 Cells

open access: yes, 2010
[[abstract]]Skin cancer is one of the common carcinomatous diseases. It is becoming increasingly common in younger populations.Recently, many reports indicated that increased intake of cruciferous vegetables may be effective in preventing the risk of ...
Liu-Wei Wu
core  

Effect of additives and food processing conditions on Benzyl glucosinolate hydrolysis products in Carica papaya [PDF]

open access: yes, 2012
Glucosinolate are sulphur-containing secondary metabolites found largely in Brassicaceae family. Glucosinolate undergoes hydrolysis readily upon cell rupture, such as cutting and cooking, by the naturally-occurring enzyme myrosinase to form mainly ...
Gayathri Nagappan
core  

Perspective on This Article from Dietary Chemopreventative Benzyl Isothiocyanate Inhibits Breast Cancer Stem Cells In Vitro and In Vivo

open access: yes, 2013
Perspective on This Article from Dietary Chemopreventative Benzyl Isothiocyanate Inhibits Breast Cancer Stem Cells In Vitro and In ...
Shivendra V. Singh (14884695)   +2 more
core   +1 more source

Benzyl Isothiocyanate: Double Trouble for Breast Cancer Cells [PDF]

open access: yesCancer Prevention Research, 2013
Abstract An inverse association between dietary intake of cruciferous vegetables and cancer risk has been established for different types of malignancies, including breast cancer. The anticarcinogenic effect of cruciferous vegetables has been attributed to chemicals with an isothiocyanate (ITC) functional moiety.
openaire   +2 more sources

Base‐Mediated Synthesis of Sulfur‐Substituted Imides using N‐(acyloxy)‐Tetrachlorophthalimides/Anhydrides and Alkyl Isothiouronium Salts

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
An efficient, scalable, and versatile base‐triggered synthesis of sulfur‐substituted imides with the utility of alkyl isothiouronium salts and masked carboxylic acids under mild reaction conditions. Imides have a vast presence in pharmaceuticals and natural products, and their synthesis generally relies on the utility of the disagreeable strong ...
Malibongwe P. Shandu   +4 more
wiley   +1 more source

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