Results 141 to 150 of about 3,145 (187)
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Reaction of pig plasma benzylamine oxidase with betaaminopropionitrile
Agents and Actions, 1985Beta-aminopropionitrile (BAPN) is an inhibitor of pig plasma benzylamine oxidase. BAPN is oxidized by benzylamine oxidase. Inhibition develops in a time-dependent fashion upon incubation of BAPN with the enzyme in the absence of substrate. The product of oxidation of BAPN by benzylamine oxidase, cyanacetaldehyde, was identified and prepared by ...
RAIMONDI, LAURA +8 more
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Development of benzylamine oxidase and monoamine oxidase A and B in man
Biochemical Pharmacology, 1980Abstract We describe the widespread distribution of the enzymes benzylamine oxidase (BzAO) and monoamine oxidase A and B (MAO A, MAO B) in human tissues at three stages of development: fetal, neonatal and adult. Relatively low activity of each is present in fetal tissues, but the specific activities of BzAO and MAO B in fetal liver are similar to ...
R, Lewinsohn, V, Glover, M, Sandler
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A benzylamine oxidase distinct from monoamine oxidase B—Widespread distribution in man and rat
Biochemical Pharmacology, 1978Abstract Benzylamine oxidase (BzAO) and monoamine oxidase type B(MAO-B) both selectively catalyse the oxidative deamination of benzylamine (Bz). We define the former as that benzylamine-metabolizing activity insensitive to 4 × 10 −4 M deprenyl, a concentration which totally inhibits all forms of MAO. Although both enzymes are widespread in human and
R, Lewinsohn +3 more
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Nature of the organic cofactor of pig plasma benzylamine oxidase
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1990The identification of the organic cofactor of pig plasma benzylamine oxidase is described. Acid hydrolysis of the enzyme in argon in the presence of phenylhydrazine (6 h at 115 degrees C in 0.027 M sulphuric acid) allowed the isolation of an adduct which was purified by HPLC and identified as phenylhydrazone of pyridoxal by spectrophotometry ...
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Purification of pig heart benzylamine oxidase.
International journal of molecular medicine, 1998A benzylamine oxidase (E.C. 1.4.3.6) has been purified from pig heart. Western blot analysis showed that the enzyme cross-reacts with a polyclonal antibody raised against homogeneous, crystalline pig plasma benzylamine oxidase (BAO). A subunit molecular mass of 97 kDa obtained by SDS electrophoresis is identical to the plasma enzyme.
, Buffoni, , Dowling, , Cambi
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Stereochemistry of Benzylamine Oxidation by Copper Amine Oxidases
Archives of Biochemistry and Biophysics, 1995Copper amine oxidases (EC 1.4.3.6) exhibit stereochemical heterogeneity in their reaction specificities. Enzymes isolated from different sources have previously been shown to catalyze the deamination of tyramine and dopamine with abstraction of the pro-R hydrogen at C-1, the pro-S hydrogen, and net nonstereo-specific protein abstraction.
G, Alton +3 more
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Benzylamine oxidase in normal and atherosclerotic human aortae
Experimental and Molecular Pathology, 1983Assays of serum benzylamine oxidase (BzAO) have led some workers to postulate a relationship between elevated BzAO activity and diseases characterized by proliferating connective tissue. The present study was designed to determine whether BzAO activity of a cellular tissue is also affected.
B E, Hayes, P T, Ostrow, D E, Clarke
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The Kinetics of Reoxidation of Reduced Benzylamine Oxidase
European Journal of Biochemistry, 1977The mechanism of reoxidation of reduced benzylamine oxidase has been investigated at different pH between 6 and 10 by steady‐state and transient‐state kinetic methods. The reoxidation process involves minimally a second‐order interaction between reduced enzyme and oxygen leading to the formation of a spectrally modified enzyme intermediate, and a ...
B, Olsson, J, Olsson, G, Pettersson
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