Results 71 to 80 of about 3,145 (187)

Tumor Diagnosis and Treatment Based on Stimuli‐Responsive Aggregation of Gold Nanoparticles

Exploration, Volume 5, Issue 3, June 2025.
This review summarizes the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment. The authors hope this review can provide a valuable reference for the further development of AuNPs clinical applications.
Xiaowei Chang, Huaiyu Wang, Xin Chen
wiley   +1 more source

Salsolinol: an Unintelligible and Double-Faced Molecule—Lessons Learned from In Vivo and In Vitro Experiments [PDF]

, 2017
Salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline) is a tetrahydroisoquinoline derivative whose presence in humans was first detected in the urine of Parkinsonian patients on l-DOPA (l-dihydroxyphenylalanine) medication.
Bugajski, Andrzej, Gil, Krzysztof, Kurnik-Łucka, Magdalena, Panula, Pertti   +3 more
core   +2 more sources

Age-related changes in benzylamine oxidase activity in rat tissues

Journal of Pharmacy and Pharmacology, 1984
AbstractBrain, liver, heart, lung, kidney and duodenum benzylamine oxidase (BZAO) activities were measured from young and old rats. Protein content was found to decrease in liver (-17%), kidney (-20%) and duodenum (-17%) but remained unchanged in brain, heart and lung of old rats compared with that of young rats.
H, Cao Danh, M, Strolin Benedetti, P, Dostert, A, Mousset   +3 more
openaire   +2 more sources

Antimicrobial Piano‐Stool and Polypyridyl Ru(II) Complexes with Thiazolhidrazinylidene‐Chroman‐2,4‐Dione: Tautomerism, Membrane Disruption, and Electron Transport Interference

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
Metalloantibiotics: A library of piano‐stool and polypyridyl Ru(II) complexes bearing thiazolhidrazinylidene‐chroman‐2,4‐diones was evaluated as metalloantibiotics. A complex is identified with a noteworthy minimum inhibitor concentration value of 3.1 μm and no toxicity in healthy eukaryotic cells.
Fatlinda Rahmani, Gozde Demirci, Youri Cortat, Aurélien Crochet, Fabio Zobi   +4 more
wiley   +1 more source

Recent Advances in Biocatalytic Promiscuity: Hydrolase-Catalyzed Reactions for Nonconventional Transformations [PDF]

, 2015
Financial support from the Spanish Ministerio de Economía y Competitividad (CTQ2013-44153-P) is grateful acknowledged. M.L.-I.
Gotor Fernández, Vicente, López Iglesias, María   +1 more
core   +2 more sources

Advances and Challenges in the Development of Immobilized Enzymes for Batch and Flow Biocatalyzed Processes

ChemSusChem, Volume 18, Issue 8, April 14, 2025.
Recent advancements in the preparation of immobilized enzymes have improved both batch and continuous flow biocatalytic processes, essential for cost‐effective, sustainable production in the fine chemicals and pharmaceutical industries. This review examines advancements in carrier‐free methods, entrapment strategies, and support‐based approaches ...
Stefania Patti, Ilaria Magrini Alunno, Sara Pedroni, Sergio Riva, Erica Elisa Ferrandi, Daniela Monti   +5 more
wiley   +1 more source

Opipramol inhibits lipolysis in human adipocytes without altering glucose uptake and differently from antipsychotic and antidepressant drugs with adverse effects on body weight control [PDF]

, 2020
Treatment with several antipsychotic drugs exhibits a tendency to induce weight gain and diabetic complications. The proposed mechanisms by which the atypical antipsychotic drug olanzapine increases body weight include central dysregulations leading to ...
Boulet, N., Carpéné, C., Fontaine, J., Garcia-barrado, M.J., Gomez-zorita, S., Grolleau, J.L., Iglesias-osma, M.C., Les, F., Mercader, J.   +8 more
core   +3 more sources

Quantum Transition State Theory for proton transfer reactions in enzymes

, 2009
We consider the role of quantum effects in the transfer of hyrogen-like species in enzyme-catalysed reactions. This study is stimulated by claims that the observed magnitude and temperature dependence of kinetic isotope effects imply that quantum ...
Abad J L, Ankerhold J, Bell R, Benderskii V A, Coleman S, Eckel J, Hasted H, Jacques P Bothma, Joel B Gilmore, Kohen A, May V, Nitzan A, Ross H McKenzie, Settle F, Weiss U   +14 more
core   +1 more source

Linking personality to larval energy reserves in rainbow trout (Oncorhynchus mykiss). [PDF]

, 2012
There is a surging interest in the evolution, ecology and physiology of personality differences. However, most of the studies in this research area have been performed in adult animals.
A Sih, AJ Frost, AM Bell, C Barr, C Deleaniz, C Summers, CM Coppens, D Nettle, D Reale, D Reale, D Reale, D Wilson, E Brännäs, E Höglund, EA Daubert, Erik Höglund, Gonzalo G. de Polavieja, HD Freeman, I Barber, I Weigensberg, J Bernardo, J Cote, J Koolhaas, J Stamps, J Vaz-Serrano, JA Stamps, JL Lukkes, JM Koolhaas, JM Koolhaas, K Lesch, K van Oers, KA Pavlov, KCF Fone, LF Jensen, M Wolf, M Wolf, MA Andersson, Madelene Åberg Andersson, N Metcalfe, NA Dochtermann, NJ Dingemanse, R Plomin, S Dall, S Einum, S Einum, S Gosling, S Gosling, S Winberg, SF de Boer, SJ Suomi, T Mousseau, T Price, T Regnier, TGG Groothuis, Ø Øverli   +54 more
core   +2 more sources

Fluorescent Probes for Analysis and Imaging of Monoamine Oxidase Activity [PDF]

Monoamine oxidases catalyze the oxidative deamination of dietary amines and amine neurotransmitters, and assist in maintaining the homeostasis of the amine neurotransmitters in the brain.
Ahn, KH, Jun, YW, Kim, D
core   +1 more source