Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration [PDF]
Ischemic stroke is the second leading cause of death worldwide. Only one moderately effective therapy exists, albeit with contraindications that exclude 90% of the patients.
Shah, Ajay M. +149 more
core +1 more source
Correlation between monoamine oxidase mRNA expression and enzymatic activity in rat tissues [PDF]
Monoamine oxidase A and B (MAO-A and -B, EC 1.4.3.4) are the major enzymes that catalyze the oxidative deamination of neurotransmitters, peripheral vasoactive amines and xenobiotics. MAO-A and -B can be distinguished by difference in substrate preference
サクライ, エイイチ +14 more
core
Neutrophil antimicrobial defense against Staphylococcus aureus. contribution of cathelicidin and the NADPH oxidase [PDF]
Neutrophils are among the most important components of the innate immune response, which provides the first line of host defense. The antimicrobial potential of neutrophils has been traditionally divided into either non-oxidative or oxidative ...
Jann, Naja
core +1 more source
Engineering the substrate specificity of galactose oxidase [PDF]
Biocatalysis, the use of enzymes to catalyse the generation of specific chemicals, has a number of advantages including high specificity, lower energy requirements and greater sustainability over an equivalent chemical process.
Chappell, Lucy
core +4 more sources
The respiratory arsenite oxidase: structure and the role of residues surrounding the Rieske cluster [PDF]
The arsenite oxidase (Aio) from the facultative autotrophic Alphaproteobacterium Rhizobium sp. NT-26 is a bioenergetic enzyme involved in the oxidation of arsenite to arsenate.
Muse Oke (452182) +56 more
core +1 more source
Stereochemistry of oxidation of benzylamine by the amine oxidase from beef plasma
2.1. Enzyme and substrates The enzyme was purified to homogeneity by a modification of method in [l] and will be detailed in [2]. The enzyme was stored as a suspension in 0.1 M Na2HP04/KH2P04 (pH 7.0) buffer containing ammonium sulphate to 0.55 saturation. Purified enzyme had spec. act.
Battersby, A.R. +3 more
openaire +2 more sources
Engineering Galactose Oxidase to Increase Expression Level in E. coli, Enhance Thermostability and Introduce Novel Activities [PDF]
For the first time, we functionally expressed the fungal glycosylated copper-containing enzyme, galactose oxidase, in Escherichia coli. The generation of fully functional GOase confirms that the formation of the unusual thioether bond is an auto ...
Sun, Lianhong
core +1 more source
Benzylamine oxidase activity in pathological states
Benzylamine oxidase (BzAO) is an amine oxidase of unknown physiological significance. However, clinical studies show that BzAO activity is elevated in the serum of patients with fibrotic disorders and during growth spurts in children.
Hayes, Barbara Elaine
core
Regulation of the microglial NADPH oxidase by neurotransmitters: implications for microglial – neuronal interactions [PDF]
Neurotransmitter dysregulation and reactive oxygen species (ROS) are a hallmark of neurodegenerative disease. Microglia, the immune cells of the CNS, express three NADPH oxidase isoforms (Nox1, Nox2 and Nox4), which produce superoxide that is used as an ...
Mead, E.L.
core
A catalytic mechanism for pig plasma benzylamine oxidase [PDF]
G, Taylor, P F, Knowles
openaire +2 more sources

