Results 61 to 70 of about 3,145 (187)
Why Leave a Job Half Done? Recent Progress in Enzymatic Deracemizations [PDF]
Financial support of this work by the Spanish MICINN (Projects CTQ2011-24237 and CTQ2013-44153) is gratefully ...
Díaz Rodríguez, Alba +2 more
core +2 more sources
Enzymic characteristics of benzylamine oxidase and monoamine oxidase in rat lung
Abstract Many studies on various tissues indicate the presence of benzylamine oxidase (BZO), and there are two forms of BZO in rat heart and aorta. Here, we compared enzymic properties of rat lung BZO and MAO and studied the possible existence of two forms of BZO.
Toshihiko Ueda +2 more
openaire +1 more source
Abstract Berzosertib is a small‐molecule ataxia telangiectasia and Rad3‐related protein inhibitor. To assess the clearance mechanism(s) of berzosertib, a Phase 1, 2‐period, open‐label study was conducted in adults with advanced solid tumors who were treated with a single intravenous dose of 210 mg/m2 berzosertib containing approximately 3 µCi of [14C ...
Jayaprakasam Bolleddula +12 more
wiley +1 more source
A catalytic mechanism for the enzyme benzylamine oxidase from pig plasma [PDF]
Initial-velocity and product-inhibition studies on the enzyme benzylamine oxidase from pig plasma indicate that the order of substrate addition and product release is benzylamine on, ammonia off, oxygen on, hydrogen peroxide off, benzaldehyde off. Ammonia, but not benzaldehyde, is released under strictly anaerobic conditions which provides independent ...
C E, Taylor +3 more
openaire +2 more sources
MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION [PDF]
Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter ...
DUCCI, FRANCESCA
core
Semicarbazide-sensitive amine oxidase (SSAO): from cell to circulation [PDF]
Semicarbazide-sensitive amine oxidase (SSAO) is a multi-functional enzyme widely present in nature. It converts primary amines into their corresponding aldehydes, while generating H(2)O(2) and NH(3).
Bagghoe, U. +3 more
core
Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B) [PDF]
Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selectiv e and irreversible MAO-B inhibitors such as L -deprenyl and rasagiline are clinically used for the t reatment of ...
Nag, Sangram
core +2 more sources
A Catalytic Mechanism for Benzylamine Oxidase from Pig Plasma [PDF]
Ammonium ion is shown to decrease the rate constants for Schiff's base formation and formation of a reduced intermediate during the catalytic cycle of benzylamine oxidase from pig plasma. The rate constant for reoxidation of the reduced intermediate is also inhibited whilst the rate constant for conversion of the oxidised enzyme form back to native ...
K D, Yadav, P F, Knowles
openaire +2 more sources
Active‐Site Titration of Pig‐Plasma Benzylamine Oxidase with Hydrazine Derivatives [PDF]
The interaction between pig plasma benzylamine oxidase and hydrazine derivatives has been investigated kinetically and spectrophotometrically. The hydrazines tested combine irreversibly to the enzyme and there is a one‐to‐one correspondence between inactivation of the enzyme and hydrazone formation with enzyme‐bound pyridoxal phosphate ...
A, Lindström, G, Pettersson
openaire +2 more sources
This review briefly highlights the construction of charge‐assisted hydrogen‐bonded organic frameworks using a variety of organic acids and organic bases, which feature different hydrogen‐bonding motifs, along with their applications, including negative linear compressibility, proton conduction, atmospheric water harvesting, gas adsorption and ...
Xian‐Xian Xiao +5 more
wiley +1 more source

