Results 41 to 50 of about 132,595 (163)
Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Integrative Insights Into DYRK1A From Molecular Function to Therapeutic Advancement
Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.At the center the 3D structure of DYRK1A has been displayed. The dual‐function of DYRK1A involved in cancer and neurodegeneration, i.e., its overexpression drives Down syndrome, neurodegenerative disease etc., and underexpression causes intellectual disability, seizures, etc.
Sampriti Paul +2 more
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Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung [PDF]
, 2014 Siglec-E is a sialic acid-binding Ig-like lectin expressed on murine myeloid cells. It has recently been shown to function as a negative regulator of ß2-integrin-dependent neutrophil recruitment to the lung following exposure to lipopolysaccharide (LPS).
Hegde, Vikas +9 more
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Drug Design, Development and Therapy, 2017 Yuh-Hwa Liu,1,2,* Yeh-Lin Lu,3,* Der-Zen Liu,4 Wen-Chi Hou5 1Division of Gastroenterology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; 2Department of General Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 3Department
Liu YH, Lu YL, Liu DZ, Hou WC
doaj
Semicarbazide-sensitive amine oxidase substrates in obesity and diabetes [PDF]
, 2010 L'obésité et le diabète sont de sérieux problèmes de santé dans les pays développés. Le développement de médicaments qui pourraient normaliser un métabolisme glucidique alteré est donc une grande nécessité actuelle.
Iffiu-Soltész, Zsuzsa
core
Thermal inactivation and conformational lock studies on glucose oxidase [PDF]
In this study, the dissociative thermal inactivation and conformational lock theories are applied for the homodimeric enzyme glucose oxidase (GOD) in order to analyze its structure.
امانی, مجتبی +4 more
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Expression and modulation of an NADPH oxidase in mammalian astrocytes [PDF]
, 2005 Amyloid β peptides generate oxidative stress in hippocampal astrocytes through a mechanism sensitive to inhibitors of the NADPH oxidase [diphenylene iodonium (DPI) and apocynin].
Abramov, A.Y. +5 more
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Enzymic characteristics of benzylamine oxidase and monoamine oxidase in rat lung
Japanese Journal of Pharmacology, 1983 Abstract Many studies on various tissues indicate the presence of benzylamine oxidase (BZO), and there are two forms of BZO in rat heart and aorta. Here, we compared enzymic properties of rat lung BZO and MAO and studied the possible existence of two forms of BZO.
Toshihiko Ueda +2 more
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The organometallic route to benzylamine type monoamine oxidase inhibitors
N-Methyl-N-(2-propynyl)piperonylamine can be simultaneously lithiated at the terminal acetylenic and at that arom. position which is flanked by both the side chain and an oxygen atom. Under carefully established conditions, the metal occupying the latter
Schlosser, Manfred, Geneste, Herve
core +1 more source
One‐Dimensional Covalent Organic Framework: Synthesis and Photoelectronic Applications
Advanced Energy and Sustainability Research, Volume 7, Issue 3, March 2026.The functional monomer structures, synthetic strategies, and the related applications of one‐dimensional covalent organic frameworks, as well as their current challenges and future development directions, have been summarized and prospected. One‐dimensional covalent organic frameworks (1D COFs) are linear porous materials constructed from organic units
Xuxin Fan +7 more
wiley +1 more source