Characterization of the Covalently Bound Anionic Flavin Radical in Monoamine Oxidase A by Electron Paramagnetic Resonance [PDF]
, 2007 It was recently suggested that partially reduced monoamine oxidase (MAO) A contains an equilibrium mixture of an anionic flavin radical and a tyrosyl radical (Rigby, S. E.; et al. J. Biol. Chem. 2005, 280, 4627-4632).
KAY CW +4 more
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Unprecedented lysyloxidase activity of Pichia pastoris benzylamine oxidase [PDF]
FEBS Letters, 1988 Benzylamine oxidase (EC 1.4.3.6) from the yeast Pichia pastoris is a 106 kDa quinoprotein containing one copper atom per molecule. It has a broad substrate specificity ranging from butylamine to peptidyl lysine in collagen and elastin. The kinetic data obtained using lysine‐containing model peptides as substrates indicate an astonishing similarity to ...
Tur, Sigmund S., Lerch, Konrad
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Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism [PDF]
, 2000 A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism.
Benda, Ellen +5 more
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Benzylamine oxidase from brain microvessels
FEBS Letters, 1983 Copper‐containing benzylamine oxidase with a specific activity of 200 units was isolated from bovine brain microvessels. It was shown that the content of the enzyme in microvessels was significantly higher as compared with large blood vessels such as heart aorta. Some physico‐chemical properties of the enzyme were determined.
Mehrabian, Z.B., Nalbandyan, R.M.
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Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure [PDF]
, 2012 Chronic liver failure leads to hyperammonemia, a central component in the pathogenesis of hepatic encephalopathy (HE); however, a correlation between blood ammonia levels and HE severity remains controversial. It is believed oxidative stress plays a role
Bosoi, Cristina R. +6 more
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Indian Heart Journal, 2016 Background: Semicarbazide-sensitive amine oxidase (SSAO; EC; 1.4.3.6.) has widespread tissue distribution, and the physiological role of SSAO is quite well known through its involvement in several pathological states.
Toshio Obata, Michiko Nakashima
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Mediators of Inflammation, 2020 Vascular adhesion protein-1 (VAP-1) is an ectoenzyme that functions as a copper-containing amine oxidase and is involved in leukocyte adhesion at sites of inflammation.
Ryo Kubota +6 more
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(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors [PDF]
, 2016 A series of (E)-3-heteroarylidenechroman-4-ones (1a-r) was designed, synthesized and investigated in vitro for their ability to inhibit the enzymatic activity of both human monoamine oxidase (hMAO) isoforms, hMAO-A and hMAO-B.
Alcaro, Stefano +6 more
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Platelet monoamine oxidase activity in diabetics.
Acta Médica Portuguesa, 1980 Platelet monoamine oxidase (MAO) activity was determined, using benzylamine as substract. Results are expressed as nM benzaldehyde/mg protein hour, at 37”. A total of 79 diabetics (40 M and 39 F) ranging in age from 3 to 70 years was studied.
Maria Azevedo +3 more
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Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus [PDF]
, 2005 Aims/hypothesis: Plasma semicarbazide-sensitive amine oxidase (SSAO) is elevated in patients with type 1 and type 2 diabetes and has been implicated in the pathophysiology of diabetic late complications. The regulation of SSAO production remains unknown.
Agerholm-Larsen, B. (B.) +6 more
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