Results 11 to 20 of about 1,475 (134)

Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives. [PDF]

Chem Biodivers
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Bindra S, Jeong WK, Kabier M, Kumar S, Sudevan ST, Vishwakarma HC, Parambi DGT, Maliyakkal N, Kumar S, Pappachen LK, Kim H, Mathew B.   +11 more
europepmc   +2 more sources

Micro-Environment Programmable Quinoline COFs for High-Performance Photocatalytic H₂O₂ Generation and Benzylamine Coupling. [PDF]

Adv Sci (Weinh)
A series of bio‐inspired quinoline‐based covalent organic frameworks (COFs) with varying substituents (‐R) are synthesized via multi‐component reactions. These substituents demonstrated a pronounced structure‐property relationship between their electronic effects (Hammett parameter, σp) and the photocatalytic H₂O₂ production rate, as well as the ...
Guo M, He C, Wu Z, Tian Y, Yang J, Wang Y, Wu H, Yang J, Xu M, Xue W, Cheng C, Li S, Zhao C.   +12 more
europepmc   +2 more sources

A Renal Clearable Probe for In Vivo Monoamine Oxidase (MAO) Detection. [PDF]

Adv Sci (Weinh)
A renal‐clearable Cy7‐based fluorogenic probe enables rapid and non‐invasive detection of monoamine oxidase (MAO) activity in vivo. Upon MAO‐mediated activation, the fluorescent product is efficiently excreted in urine, allowing direct quantification of enzyme overexpression.
Domínguez M, Azorín-Soriano D, Lérida-Viso A, García-Fleitas J, Soriano-Teruel PM, Beatty JS, Rodrigo-Martínez P, Arroyo P, Rojas-Vázquez S, Fariñas I, Sancenón F, Blandez JF, García-Fernández A, Martínez-Máñez R.   +13 more
europepmc   +2 more sources

Nanomaterial Integration at Liquid-Liquid Interfaces for Green Catalysis. [PDF]

Adv Mater
Functional nanomaterials assembled at liquid–liquid interfaces create dual‐role platforms serving as emulsion stabilizers and catalytic sites, offering enhanced reaction kinetics with improved catalyst recovery and recyclability. This review examines design strategies, structure‐performance relationships, and industrial implementation prospects of ...
Seo B, Shin J, Jang M, Choi K, Pang T, Zhong F, Kim JW.   +6 more
europepmc   +2 more sources

Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1

Mediators of Inflammation, 2020
Vascular adhesion protein-1 (VAP-1) is an ectoenzyme that functions as a copper-containing amine oxidase and is involved in leukocyte adhesion at sites of inflammation.
Ryo Kubota, Michael J. Reid, Kuo Lee Lieu, Mark Orme, Christine Diamond, Niklas Tulberg, Susan H. Henry   +6 more
doaj   +1 more source

Platelet monoamine oxidase activity in diabetics.

Acta Médica Portuguesa, 1980
Platelet monoamine oxidase (MAO) activity was determined, using benzylamine as substract. Results are expressed as nM benzaldehyde/mg protein hour, at 37”. A total of 79 diabetics (40 M and 39 F) ranging in age from 3 to 70 years was studied.
Maria Azevedo, Francisca Fernandes, Pedro Lisboa, Carlos Manso   +3 more
doaj   +1 more source

The presence of an inhibitor of benzylamine oxidase in human blood plasma [PDF]

Biochemical Journal, 1983
The presence of an inhibitor of benzylamine oxidase in human blood plasma was observed. It may be removed by use of either a DEAE-cellulose column or a Sephadex G-200 column.
F, Buffoni, G, Banchelli, G, Ignesti, R, Pirisino, L, Raimondi   +4 more
openaire   +2 more sources

Oral Administration of Semicarbazide Limits Weight Gain together with Inhibition of Fat Deposition and of Primary Amine Oxidase Activity in Adipose Tissue

Journal of Obesity, 2011
An enzyme hitherto named semicarbazide-sensitive amine oxidase (SSAO), involved in the oxidation of primary amines, is abundantly expressed in adipocytes.
Josep Mercader, Zsuzsa Iffiú-Soltész, Sandy Bour, Christian Carpéné   +3 more
doaj   +1 more source

Effects of semicarbazide-sensitive amine oxidase inhibitors on morphology of aorta and kidney in diabetic rats

BMC Endocrine Disorders, 2019
Background The present study aimed to investigate the inhibitory effects of aminoguanidine (AG) and 2-bromoethylamine (2-BEA) on the semicarbazide-sensitive amine oxidase (SSAO) activity both in vitro and in vivo, and the prevention role of AG and 2-BEA ...
Chaosheng Li, Zhenhua Wang, Xiaoli Li, Jun Chen   +3 more
doaj   +1 more source

Merging Biocatalysis and Chemocatalysis in Flow: State‐of‐the‐Art and Future Directions for Sustainable Synthesis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis, Matteo Damian, Francesco G. Mutti   +2 more
wiley   +2 more sources