Results 11 to 20 of about 3,145 (187)

Effects of Chemical Structures Interacting with Amine Oxidases on Glucose, Lipid and Hydrogen Peroxide Handling by Human Adipocytes [PDF]

Molecules, 2022
Benzylamine is a natural molecule present in food and edible plants, capable of activating hexose uptake and inhibiting lipolysis in human fat cells.
Christian Carpéné, Pénélope Viana, Zsuzsa Iffiú-Soltesz, Pál Tapolcsányi, Anna Ágota Földi, Péter Mátyus, Petra Dunkel   +6 more
doaj   +2 more sources

Oral Administration of Semicarbazide Limits Weight Gain together with Inhibition of Fat Deposition and of Primary Amine Oxidase Activity in Adipose Tissue [PDF]

Journal of Obesity, 2011
An enzyme hitherto named semicarbazide-sensitive amine oxidase (SSAO), involved in the oxidation of primary amines, is abundantly expressed in adipocytes.
Josep Mercader, Zsuzsa Iffiú-Soltész, Sandy Bour, Christian Carpéné   +3 more
doaj   +2 more sources

Micro-Environment Programmable Quinoline COFs for High-Performance Photocatalytic H₂O₂ Generation and Benzylamine Coupling. [PDF]

Adv Sci (Weinh)
A series of bio‐inspired quinoline‐based covalent organic frameworks (COFs) with varying substituents (‐R) are synthesized via multi‐component reactions. These substituents demonstrated a pronounced structure‐property relationship between their electronic effects (Hammett parameter, σp) and the photocatalytic H₂O₂ production rate, as well as the ...
Guo M, He C, Wu Z, Tian Y, Yang J, Wang Y, Wu H, Yang J, Xu M, Xue W, Cheng C, Li S, Zhao C.   +12 more
europepmc   +2 more sources

Properties of a cryptic lysyl oxidase from haloarchaeon Haloterrigena turkmenica [PDF]

PeerJ, 2019
Background Lysyl oxidases (LOX) have been extensively studied in mammals, whereas properties and functions of recently found homologues in prokaryotic genomes remain enigmatic. Methods LOX open reading frame was cloned from Haloterrigena turkmenica in an
Nikolay B. Pestov, Daniel V. Kalinovsky, Tatyana D. Larionova, Alia Z. Zakirova, Nikolai N. Modyanov, Irina A. Okkelman, Tatyana V. Korneenko   +6 more
doaj   +2 more sources

Novel Facet of an Old Dietary Molecule? Direct Influence of Caffeine on Glucose and Biogenic Amine Handling by Human Adipocytes

Molecules, 2021
Caffeine is a plant alkaloid present in food and beverages consumed worldwide. It has high lipid solubility with recognized actions in the central nervous system and in peripheral tissues, notably the adipose depots.
Wiem Haj Ahmed, Nathalie Boulet, Anaïs Briot, Barry J. Ryan, Gemma K. Kinsella, Jeffrey O’Sullivan, Francisco Les, Josep Mercader-Barceló, Gary T. M. Henehan, Christian Carpéné   +9 more
doaj   +1 more source

Development and Clinical Application of Positron Emission Tomography Imaging Agents for Monoamine Oxidase B

Frontiers in Neuroscience, 2022
Monoamine oxidase B (MAO-B) is a high-density protein in the brain mainly found on outer mitochondrial membranes, primarily in astroglia, but additionally in serotonergic neurons and in the substantia nigra in the midbrain.
Jeffrey H. Meyer, Jeffrey H. Meyer, Jeffrey H. Meyer, Joeffre Braga, Joeffre Braga   +4 more
doaj   +1 more source

Functional modulation of vascular adhesion protein-1 by a novel splice variant. [PDF]

PLoS ONE, 2013
Vascular Adhesion Protein-1 (VAP-1) is an endothelial adhesion molecule belonging to the primary amine oxidases. Upon inflammation it takes part in the leukocyte extravasation cascade facilitating transmigration of leukocytes into the inflamed tissue ...
Sam Kaitaniemi, Kirsi Grön, Heli Elovaara, Marko Salmi, Sirpa Jalkanen, Kati Elima   +5 more
doaj   +1 more source

Synthesis, in vitro enzyme activity and molecular docking studies of new benzylamine-sulfonamide derivatives as selective MAO-B inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Many studies have been conducted on the selective inhibition of human monoamine oxidase B (hMAO-B) enzyme using benzylamine-sulphonamide derivatives. Using various chemical modifications on BB-4h, which was reported previously by our team and showed a ...
Begüm Nurpelin Sağlık, Derya Osmaniye, Ulviye Acar Çevik, Serkan Levent, Betül Kaya Çavuşoğlu, Özlem Atlı Eklioğlu, Yusuf Özkay, Ali Savaş Koparal, Zafer Asım Kaplancıklı   +8 more
doaj   +1 more source

Methylxanthines Inhibit Primary Amine Oxidase and Monoamine Oxidase Activities of Human Adipose Tissue

Medicines, 2020
Background: Methylxanthines including caffeine and theobromine are widely consumed compounds and were recently shown to interact with bovine copper-containing amine oxidase.
Wiem Haj Ahmed, Cécile Peiro, Jessica Fontaine, Barry J. Ryan, Gemma K. Kinsella, Jeff O’Sullivan, Jean-Louis Grolleau, Gary T.M. Henehan, Christian Carpéné   +8 more
doaj   +1 more source

Metabolic Effects of Oral Phenelzine Treatment on High-Sucrose-Drinking Mice [PDF]

, 2018
Phenelzine has been suggested to have an antiobesity effect by inhibiting de novo lipogenesis, which led us to investigate the metabolic effects of oral chronic phenelzine treatment in high-sucrose-drinking mice.
Carpéné, Christian, Chaplin, Alice, Gómez Zorita, Saioa, Mercader, Josep   +3 more
core   +2 more sources