Results 1 to 10 of about 1,475 (134)

Effects of Chemical Structures Interacting with Amine Oxidases on Glucose, Lipid and Hydrogen Peroxide Handling by Human Adipocytes [PDF]

Molecules, 2022
Benzylamine is a natural molecule present in food and edible plants, capable of activating hexose uptake and inhibiting lipolysis in human fat cells.
Christian Carpéné, Pénélope Viana, Zsuzsa Iffiú-Soltesz, Pál Tapolcsányi, Anna Ágota Földi, Péter Mátyus, Petra Dunkel   +6 more
doaj   +2 more sources

Benzylamine oxidase from brain microvessels

FEBS Letters, 1983
Copper‐containing benzylamine oxidase with a specific activity of 200 units was isolated from bovine brain microvessels. It was shown that the content of the enzyme in microvessels was significantly higher as compared with large blood vessels such as heart aorta. Some physico‐chemical properties of the enzyme were determined.
R M Nalbandyan
exaly   +3 more sources

Properties of a cryptic lysyl oxidase from haloarchaeon Haloterrigena turkmenica [PDF]

PeerJ, 2019
Background Lysyl oxidases (LOX) have been extensively studied in mammals, whereas properties and functions of recently found homologues in prokaryotic genomes remain enigmatic. Methods LOX open reading frame was cloned from Haloterrigena turkmenica in an
Nikolay B. Pestov, Daniel V. Kalinovsky, Tatyana D. Larionova, Alia Z. Zakirova, Nikolai N. Modyanov, Irina A. Okkelman, Tatyana V. Korneenko   +6 more
doaj   +2 more sources

Novel Facet of an Old Dietary Molecule? Direct Influence of Caffeine on Glucose and Biogenic Amine Handling by Human Adipocytes

Molecules, 2021
Caffeine is a plant alkaloid present in food and beverages consumed worldwide. It has high lipid solubility with recognized actions in the central nervous system and in peripheral tissues, notably the adipose depots.
Wiem Haj Ahmed, Nathalie Boulet, Anaïs Briot, Barry J. Ryan, Gemma K. Kinsella, Jeffrey O’Sullivan, Francisco Les, Josep Mercader-Barceló, Gary T. M. Henehan, Christian Carpéné   +9 more
doaj   +1 more source

Development and Clinical Application of Positron Emission Tomography Imaging Agents for Monoamine Oxidase B

Frontiers in Neuroscience, 2022
Monoamine oxidase B (MAO-B) is a high-density protein in the brain mainly found on outer mitochondrial membranes, primarily in astroglia, but additionally in serotonergic neurons and in the substantia nigra in the midbrain.
Jeffrey H. Meyer, Jeffrey H. Meyer, Jeffrey H. Meyer, Joeffre Braga, Joeffre Braga   +4 more
doaj   +1 more source

Functional modulation of vascular adhesion protein-1 by a novel splice variant. [PDF]

PLoS ONE, 2013
Vascular Adhesion Protein-1 (VAP-1) is an endothelial adhesion molecule belonging to the primary amine oxidases. Upon inflammation it takes part in the leukocyte extravasation cascade facilitating transmigration of leukocytes into the inflamed tissue ...
Sam Kaitaniemi, Kirsi Grön, Heli Elovaara, Marko Salmi, Sirpa Jalkanen, Kati Elima   +5 more
doaj   +1 more source

Synthesis, in vitro enzyme activity and molecular docking studies of new benzylamine-sulfonamide derivatives as selective MAO-B inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Many studies have been conducted on the selective inhibition of human monoamine oxidase B (hMAO-B) enzyme using benzylamine-sulphonamide derivatives. Using various chemical modifications on BB-4h, which was reported previously by our team and showed a ...
Begüm Nurpelin Sağlık, Derya Osmaniye, Ulviye Acar Çevik, Serkan Levent, Betül Kaya Çavuşoğlu, Özlem Atlı Eklioğlu, Yusuf Özkay, Ali Savaş Koparal, Zafer Asım Kaplancıklı   +8 more
doaj   +1 more source

Methylxanthines Inhibit Primary Amine Oxidase and Monoamine Oxidase Activities of Human Adipose Tissue

Medicines, 2020
Background: Methylxanthines including caffeine and theobromine are widely consumed compounds and were recently shown to interact with bovine copper-containing amine oxidase.
Wiem Haj Ahmed, Cécile Peiro, Jessica Fontaine, Barry J. Ryan, Gemma K. Kinsella, Jeff O’Sullivan, Jean-Louis Grolleau, Gary T.M. Henehan, Christian Carpéné   +8 more
doaj   +1 more source

Effect of pH on the Transient Reduction of Pig-Plasma Benzylamine Oxidase by Benzylamine Derivatives [PDF]

European Journal of Biochemistry, 1976
1. The transient kinetics of reduction of the 470-nm absorption band in benzylamine oxidase by substrate at different pH values between 6 and 10 have been studied by stopped-flow techniques, and substituent effects on kinetic parameters for the reduction process have been examined using a series of ring-substituted benzylamine derivatives as the ...
A, Lindström, B, Olsson, J, Olsson, G, Pettersson   +3 more
openaire   +2 more sources

Evidence for existence of thyroid hormone inducible semicarbazide-sensitive amine oxidase (SSAO) in rat heart cytosol

Indian Heart Journal, 2016
Background: Semicarbazide-sensitive amine oxidase (SSAO; EC; 1.4.3.6.) has widespread tissue distribution, and the physiological role of SSAO is quite well known through its involvement in several pathological states.
Toshio Obata, Michiko Nakashima
doaj   +1 more source