Sulfate radical anion-induced benzylic oxidation of N-(arylsulfonyl)benzylamines to N-arylsulfonylimines [PDF]
Beilstein Journal of Organic Chemistry, 2023 A mild, operationally convenient, and practical method for the synthesis of synthetically useful N-arylsulfonylimines from N-(arylsulfonyl)benzylamines using K2S2O8 in the presence of pyridine as a base is reported herein. In addition, a “one-pot” tandem
Joydev K. Laha +2 more
doaj +2 more sources
Molecules, 2022 We developed a straightforward synthetic route to pharmacologically important 1,5-substituted pyrrolidin-2-ones from donor–acceptor cyclopropanes bearing an ester group as one of the acceptor substituents.
Maksim A. Boichenko +9 more
doaj +2 more sources
Bio-inspired manganese-catalyzed deaminative hydroxylation of benzyl amines to corresponding alcohols [PDF]
Nature CommunicationsDirect conversion of amines to corresponding alcohols is challenging even under harsh reaction conditions. Inspired by enzymatic transamination, we present a transamination borrowing-hydrogen strategy that enables the direct and selective Mn-catalyzed ...
Jiale Ji +6 more
doaj +2 more sources
Direct asymmetric α C(sp 3 )‒H alkylation of benzylamines with MBH acetates enabled by bifunctional pyridoxal catalysts [PDF]
Nature CommunicationsOrganocatalytic allylic substitution of Morita-Baylis-Hillman (MBH) adducts is widely regarded as one of the most powerful transformations in organic synthesis.
Jiayao Chen +7 more
doaj +2 more sources
Photocatalytic Phenylmethylamine Coupling Reaction of Organic–Inorganic Composites Based on Benzothiophene Polymers and TiO2 [PDF]
NanomaterialsBenzothiophene polymers, as a class of novel organic semiconductor materials, exhibit significant potential in the field of photocatalysis due to their broad light-responsive range and tunable energy level structures.
Xin Li +9 more
doaj +2 more sources
Molecules, 2017 An efficient base-catalyzed synthesis of arylated pyridines has been disclosed. This reaction involving conjugated acetylenes and substituted benzylamines proceeded smoothly, giving rise to tri-aryl substituted pyridines which are biologically relevant ...
Mengping Guo +5 more
doaj +2 more sources
Electrocatalytic hydrogenation of cyanoarenes, nitroarenes, quinolines, and pyridines under mild conditions with a proton-exchange membrane reactor [PDF]
Beilstein Journal of Organic ChemistryAn electrocatalytic hydrogenation of cyanoarenes, nitroarenes, quinolines, and pyridines using a proton-exchange membrane (PEM) reactor was developed. Cyanoarenes were then reduced to the corresponding benzylamines at room temperature in the presence of ...
Koichi Mitsudo +6 more
doaj +2 more sources
Benzylamines: synthesis and evaluation of antimycobacterial properties
Journal of Medicinal Chemistry, 1984 The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (19, MIC 10.2 micrograms/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 micrograms/mL), and N-butyl-3,
W R, Meindl +3 more
openaire +3 more sources
NiH-catalyzed asymmetric hydroarylation of N-acyl enamines to chiral benzylamines
Nature Communications, 2021 Chiral benzylamines are found in many pharmacologically active molecules. Here, the authors report an enantio- and regio-selective reductive hydroarylation of N-acyl enamines with a NiH/chiral bis-imidazoline catalytic system affording a range of ...
Yuli He +3 more
doaj +1 more source
Benzobicyclo[3.2.1]octene Derivatives as a New Class of Cholinesterase Inhibitors
Molecules, 2020 A library of amine, oxime, ether, epoxy and acyl derivatives of the benzobicyclo[3.2.1]octene were synthesized and evaluated as inhibitors of both human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).
Tena Čadež +6 more
doaj +1 more source