Results 31 to 40 of about 3,554 (196)

Synthesis of Spiro Pyrrolidines From the Addition of Schiff Bases to -Arylidene Cyclohexanones [PDF]

مجلة التربية والعلم, 2008
A series of -arylidene cyclohexanones (1-4) had been prepared via Claisen-Schmidt condensation, while other series of N-arylidene benzylamines (Schiff bases 5-10) had also been synthesized by equimolar addition.
A Al-Hamdany, A Mustafa, ِA Hamza
doaj   +1 more source

Synthesis of Novel Pyrazinamide Derivatives Based on 3-Chloropyrazine-2-carboxamide and Their Antimicrobial Evaluation

Molecules, 2017
Aminodehalogenation of 3-chloropyrazine-2-carboxamide with variously substituted benzylamines yielded a series of fifteen 3-benzylaminopyrazine-2-carboxamides. Four compounds possessed in vitro whole cell activity against Mycobacterium tuberculosis H37Rv
Ondrej Jandourek, Marek Tauchman, Pavla Paterova, Klara Konecna, Lucie Navratilova, Vladimir Kubicek, Ondrej Holas, Jan Zitko, Martin Dolezal   +8 more
doaj   +1 more source

Allylamines, Benzylamines, and Fungal Cell Permeability: A Review of Mechanistic Effects and Usefulness against Fungal Pathogens

Membranes, 2022
Allylamines, naftifine and terbinafine, and the benzylamine, butenafine, are antifungal agents with activity on the fungal cell membrane. These synthetic compounds specifically inhibit squalene epoxidase, a key enzyme in fungal sterol biosynthesis.
Dalal Hammoudi Halat, Samar Younes, Nisreen Mourad, Mohamad Rahal   +3 more
doaj   +1 more source

A metal-free approach for the synthesis of amides/esters with pyridinium salts of phenacyl bromides via oxidative C–C bond cleavage

Beilstein Journal of Organic Chemistry, 2019
An efficient, simple, and metal-free synthetic approach for the N- and O-benzoylation of various amines/benzyl alcohols with pyridinium salts of phenacyl bromides is demonstrated to generate the corresponding amides and esters.
Kesari Lakshmi Manasa, Yellaiah Tangella, Namballa Hari Krishna, Mallika Alvala   +3 more
doaj   +1 more source

Characterization of a Putrescine Transaminase From Pseudomonas putida and its Application to the Synthesis of Benzylamine Derivatives

Frontiers in Bioengineering and Biotechnology, 2018
The reductive amination of prochiral ketones using biocatalysts has been of great interest to the pharmaceutical industry in the last decade for integrating novel strategies in the production of chiral building blocks with the intent of minimizing impact
James L. Galman, Deepankar Gahloth, Fabio Parmeggiani, Iustina Slabu, David Leys, Nicholas J. Turner   +5 more
doaj   +1 more source

Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines

Nature Communications, 2020
Chiral 1,2-diamines are useful chemicals used as ligands in asymmetric catalysis. Here, the authors report a copper(I)-catalyzed asymmetric α-addition of ketimines derived from trifluoroacetophenone and 2- or 4-NO2-benzylamines to aldimines, affording a ...
Xu-Cheng Gan, Cheng-Yuan Zhang, Feng Zhong, Ping Tian, Liang Yin   +4 more
doaj   +1 more source

Fluorinated Analogues of Lepidilines A and C: Synthesis and Screening of Their Anticancer and Antiviral Activity

Molecules, 2022
Starting with fluorinated benzylamines, a series of 2-unsubstituted imidazole N-oxides was prepared and subsequently deoxygenated in order to prepare the corresponding imidazoles.
Grzegorz Mlostoń, Mateusz Kowalczyk, Małgorzata Celeda, Marcin Jasiński, Marta Denel-Bobrowska, Agnieszka B. Olejniczak   +5 more
doaj   +1 more source

One‐Pot Biphasic Photocatalytic CO2‐to‐Carbonylation Cascades

Angewandte Chemie, EarlyView.
Bioinspired biphasic compartmentalization enables one‐pot cascades where photocatalytic CO2 reduction generates CO for carbonylative cross‐couplings to synthesize complex organic products, including a pharmaceutical. ABSTRACT Photosynthesis compartmentalizes reactions across the thylakoid membrane in vivo to upcycle CO2 into complex chemicals that are ...
Sampurna Mitra, David M. Vahey, Shannon A. Bonke, Erwin Reisner   +3 more
wiley   +2 more sources

Direct Palladium-Catalyzed Ortho-Arylation of Benzylamines

, 2016
Unsubstituted benzylamines and N-methylbenzylamine can be ortho-arylated under palladium catalysis at 130 °C.
Anna Lazareva (2236426), Olafs Daugulis (1322985)   +1 more
core   +2 more sources

Neue Methode zur reduktiven Desaminierung primärer aliphatischer Amine

CHIMIA, 1988
A new method for reductive deamination of primary aliphatic amines via tributyltin hydride reduction of aromatic imidoyl chlorides is reported. Good yields of hydrocarbons were obtained from benzylamines and cyclohexylamine, but not from 1-alkylamines.
Thomas Wirth, Christoph Rüchardt
doaj   +1 more source