Results 151 to 160 of about 1,130 (187)
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Antispasmodic Activity of Benzylisoquinoline Alkaloids Analogous to Papaverine
Planta Medica, 1993In vitro, reticuline, norarmepavine, coclaurine, and papaverine competitively antagonize the uterine muscular contractions induced by acetylcholine and calcium. The antagonism is more efficient for the alkaloid coclaurine which is even stronger than papaverine.
M L, Martin +5 more
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Evolutionary and cellular webs in benzylisoquinoline alkaloid biosynthesis
Current Opinion in Biotechnology, 2008Alkaloids are a group of approximately 12,000 low molecular weight and nitrogenous secondary metabolites found in 20% of plant species. Their potent biological activity suggests that alkaloids function as defense compounds. Benzylisoquinoline alkaloids (BIAs) are derived from tyrosine and are diversified by an intricate biochemical network of ...
David K, Liscombe, Peter J, Facchini
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Nomenclature of benzylisoquinoline and related alkaloids
Chemistry of Natural Compounds, 1981A classification of the bisbenzylisoquinoline, benzylisoquinoline, and related alkaloids is proposed which is based on the biogenetic characteristics of these alkaloids.
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An Overview on Benzylisoquinoline Derivatives with Dopaminergic and Serotonergic Activities
Current Medicinal Chemistry, 2009Dopamine and serotonin are important neurotransmitters in the mammalian central nervous system (CNS) involved in numerous physiological and behavioural disorders such as schizophrenia, major depression, anxiety, Parkinson's and Huntington's diseases, and attention deficit hyperactivity disorder.
N, Cabedo +3 more
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Inhibition of nonenzymic lipid peroxidation by benzylisoquinoline alkaloids
Free Radical Biology and Medicine, 1992A group of benzylisoquinoline alkaloids, including five simple benzylisoquinolines, three phtalideisoquinolines, six aporphines, three protoberberines, and two benzophenanthridines, have been studied as inhibitors of lipid peroxidation stimulated by Fe2+/cysteine in rat liver microsomal fractions.
L A, Martínez +3 more
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Benzylisoquinoline Alkaloids from Anisocycla jollyana Leaves
Journal of Natural Products, 1995A new bisbenzylisoquinoline alkaloid, (+)-limacusine-2'-β-N-oxide [1], was isolated from the leaves of Anisocycla jollyana, along with nine known alkaloids : (-)-2'-norlimacine, (-)-2-norlimacine, (-)-limacine, (-)-limacine-2'-β-N-oxide, (+)-homoaromaline, (+)-trilobine, (+)-isotrilobine, (+)-dehydro-1,2-telobine, and (+)-remrefidine.
Kanyinda Wa Banyingela, Banyingela +2 more
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Secondary Plant Substances · Benzylisoquinoline Alkaloids
1989Within the class of alkaloids, the isoquinoline alkaloids are of particular interest, due to their enormous potential chemical variations of the basic precursor molecules and on the other hand because it comprises some of the most important drugs for therapy and euphoria (e.g., morphine and its chemical derivatives, papaverine, berberine dimeric ...
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[Enzymology of production of benzylisoquinoline alkaloids].
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2005This review paper summarizes the current knowledge of enzymes participating in the production of benzylisoquinoline alkaloids. This group of alkaloids comprises, e.g., morphine, codeine, thebaine, and sanginarine, which have an irreplaceable position in pharmaceutical practice. For the time being, chemists have not managed to prepare them synthetically
A, Bilková, F, Bilka, L, Bezáková
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Antimicrobial activity of benzylisoquinoline alkaloids.
Die Pharmazie, 1987The antimicrobial in vitro activity of 14 benzylisoquinoline alkaloids was investigated by agar diffusion and agar dilution methods against several genera of microorganisms that included Streptococcus, Staphylococcus, Bacillus, Lysteria, Escherichia, Salmonella, Klebsiella, Pseudomonas, Enterobacter, Serratia, Shigella, Mycobacterium and Candida ...
A, Villar +4 more
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Enzymology of Benzylisoquinoline Alkaloid Formation
1985The largest group of naturally occurring alkaloids comprises compounds based on the tetrahydroisoquinoline nucleus. A multitude of structural types derived from this nucleus is found in the plant kingdom (Shamma 1972, Shamma and Moniot 1978). A great number of biosynthetic hypotheses based on in vivo investigations has been proposed to explain this ...
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