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Berberine: Complex with DNA

Science, 1969
A complex of calf-thymus DNA with berberine sediments in the analytical ultracentrifuge. The DNA produced systematic changes in the absorption spectrum of berberine which suggest that single alkaloid molecules bind to DNA. Flow dichroism of purines and pyrimidines and of berberine in the complex with DNA had the same signs and magnitudes.
A K, Krey, F E, Hahn
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HEPATOBILIARY EXCRETION OF BERBERINE

Drug Metabolism and Disposition, 2004
Berberine is a bioactive herbal ingredient isolated from the roots and bark of Berberis aristata or Coptis chinensis. To investigate the detailed pharmacokinetics of berberine and its mechanisms of hepatobiliary excretion, an in vivo microdialysis coupled with high-performance liquid chromatography was performed.
Pi-Lo, Tsai, Tung-Hu, Tsai
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Cardiovascular Actions of Berberine

Cardiovascular Drug Reviews, 2001
ABSTRACTBerberine, is an alkaloid fromHydrastis canadensisL., Chinese herb Huanglian, and many other plants. It is widely used in traditional Chinese medicine as an antimicrobial in the treatment of dysentery and infectious diarrhea. This manuscript describes cardiovascular effects of berberine and its derivatives, tetrahydroberberine and 8 ...
C W, Lau   +4 more
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Berberine.

Alternative medicine review : a journal of clinical therapeutic, 2000
Berberine is a plant alkaloid with a long history of medicinal use in both Ayurvedic and Chinese medicine. It is present in Hydrastis canadensis (goldenseal), Coptis chinensis (Coptis or goldenthread), Berberis aquifolium (Oregon grape), Berberis vulgaris (barberry), and Berberis aristata (tree turmeric).
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Isolation of berberine

Chemistry of Natural Compounds, 1974
The conditions for the extraction and isolation from the wood and bark of the roots ofBerberis oblonga have been studied.
M. M. Tadzhibaev   +3 more
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Biochemical effects of berberine

Biochemical Pharmacology, 1979
Abstract The benzodioxoloquinolizine alkaloid berberine inhibited the biosyntheses of UNA, RNA, proteins and lipids, as well as the oxidation of glucose [14C] to 14CO2, when incubated with S 180 cells in vitro. The synthesis of proteins and of RNA was the most sensitive of these parameters to the action of berberine.
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Berberine

Reactions Weekly, 2019
Ajay Srivastava   +3 more
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Berberine and berberine nanoformulations in cancer therapy: Focusing on lung cancer

Phytotherapy Research
AbstractLung cancer is the second most prevalent cancer and ranks first in cancer‐related death worldwide. Due to the resistance development to conventional cancer therapy strategies, including chemotherapy, radiotherapy, targeted therapy, and immunotherapy, various natural products and their extracts have been revealed as alternatives. Berberine (BBR),
Chou‐Yi Hsu   +7 more
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Berberine

Reactions Weekly, 2018
Lian-Hua Fang, Jin-Hua Wang, Guan-Hua Du
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