Family quality‐of‐life burden in chronic spontaneous urticaria: A multicentre study
Poor control of chronic spontaneous urticaria (CSU) significantly worsens family members' quality of life, especially in emotional, physical, and social domains. Higher disease severity was linked to increased caregiving burden and household expenditures, highlighting the need for family‐centred CSU care and support across diverse global populations ...
Beatrice Martinez Zugaib Abdalla +33 more
wiley +1 more source
Contamination status and accumulation characteristics of heavy metals and arsenic in five seabird species from the central Bering Sea. [PDF]
Ishii C +7 more
europepmc +1 more source
Litifilimab efficacy on skin outcomes in cutaneous lupus erythematosus in the Phase 2 LILAC study
Our findings show that greater proportions of litifilimab‐treated participants than placebo experienced 20%, 50%, 70% or 90% improvements in CLASI‐A score from baseline and CLASI‐A scores of 0–1 or 0–3. Similar results were observed using physician global assessments, supporting the Phase 2 LILAC study primary analysis in CLE.
Victoria P. Werth +8 more
wiley +1 more source
The effects of a constructed closure of the Bering Strait on AMOC tipping behavior. [PDF]
Soons J, Dijkstra HA.
europepmc +1 more source
Bimekizumab efficacy using IHS4 outcomes in hidradenitis suppurativa: Results from BE HEARD I and II
The majority of bimekizumab‐treated patients shifted from severe to mild and moderate IHS4 stages, and nearly 25% achieved an IHS4 of 0 by Week 48. Bimekizumab led to clinically meaningful improvements across IHS4 outcome measures. These data highlight an opportunity to address the need for effective treatments against draining tunnels.
Thrasyvoulos Tzellos +15 more
wiley +1 more source
On the Shrimp Resources of the Bering Sea
Ituso KUBO, Hiroshi IIDA
openaire +1 more source
Tocilizumab for severe and refractory mucous membrane pemphigoid
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt +20 more
wiley +1 more source
Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran +2 more
wiley +1 more source
Polar cod Boreogadus saida occurrence is driven by temperature at the margin of its distribution
Abstract With a warming Arctic, suitable habitat for polar cod Boreogadus saida (Lepechin 1774) is predicted to decrease. We investigated the changes in distribution of polar cod on the southern limit of its distribution in the Atlantic Ocean (around Iceland) during both autumn and spring after a recent period of warming in the area.
James Kennedy, Christophe Pampoulie
wiley +1 more source
Abstract Atlantic herring Clupea harengus are total spawners that exhibit a large degree of reproductive plasticity and have substantial intra‐annual variation in their energetic condition. Recent research suggests that the species may be declining in energetic condition in the northwest Atlantic Ocean from the few historical records, but comparisons ...
Joseph B. Warren +2 more
wiley +1 more source

