Results 51 to 60 of about 3,445 (263)

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise   +3 more
wiley   +1 more source

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

open access: yesBiological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief   +4 more
wiley   +1 more source

Mass Occurrence of Pacific Copepods in the Southern Chukchi Sea During Summer: Implications of the High-Temperature Bering Summer Water

open access: yesFrontiers in Marine Science, 2020
The Bering Strait is the only gateway to the Chukchi Sea from the Pacific Ocean and is a major route of Pacific water inflow. We recently investigated the occurrence of Pacific copepod species along with the warming of the Chukchi Sea and sought to ...
Jee-Hoon Kim   +8 more
doaj   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Basin‐Wide Shift in Bowhead Whale Migration in the Pacific Arctic

open access: yesGeophysical Research Letters
In a rapidly changing Arctic, multiple lines of evidence suggest that bowhead whale migration is changing. To explore these changes further, we used passive acoustic data to examine bowhead whale presence in the western Beaufort Sea (12 years) and ...
Angela R. Szesciorka   +2 more
doaj   +1 more source

Platelet FcɣRIIa Expression Refines Clinical Risk Assessment After Myocardial Infarction

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In patients with myocardial infarction (MI), quantifying expression of platelet FcɣRIIa (pFCG) stratifies risk of subsequent MI, stroke, and death. Aims Assess the prognostic implications of clinical risk alone and in combination with the pFCG test.
David J. Schneider   +9 more
wiley   +1 more source

Seasonal patterns and interannual variations of atmospheric circulation over the Bering Sea in 1995–2022

open access: yesИзвестия ТИНРО
Mean patterns of atmospheric circulation over the Bering Sea in 4 seasons: winter (January-March), spring (April-June), summer (July-September) and autumn (OctoberDecember) are described using the author’s typification of synoptic situations.
S. Yu. Glebova
doaj   +1 more source

Generalized assessments of composition, quantitative distribution and biomass of benthic macrofauna on the shelf and slope in the North-West Pacific

open access: yesИзвестия ТИНРО, 2015
Quantitative information on the bottom macrofauna of the continental shelf and slope down to the depth 2025 m is generalized for the Far East of Russia and the adjacent waters of North Korea and Japan (in total 32,700 bottom trawls obtained in 224 ...
Vyacheslav P. Shuntov, Igor V. Volvenko
doaj   +1 more source

Corporate Social Responsibility as a Stakeholder Signal: Fairness and Belonging as Pathways to Job Satisfaction and Commitment

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Existing research shows that corporate social responsibility (CSR) benefits firms in terms of return on investment, customer satisfaction, and reputation; however, limited attention is given to employees as internal stakeholders. Drawing on Stakeholder Theory, Social Exchange Theory, and Social Identity Theory, this study investigates how CSR ...
Mengyun Zhang   +4 more
wiley   +1 more source

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