Results 61 to 70 of about 2,361,484 (180)

The GPIb-IX complex on platelets: insight into its novel physiological functions affecting immune surveillance, hepatic thrombopoietin generation, platelet clearance and its relevance for cancer development and metastasis

Experimental Hematology & Oncology, 2022
The glycoprotein (GP) Ib-IX complex is a platelet receptor that mediates the initial interaction with subendothelial von Willebrand factor (VWF) causing platelet arrest at sites of vascular injury even under conditions of high shear.
Gerd Bendas, Martin Schlesinger
doaj   +1 more source

GPIbα is the driving force of hepatic thrombopoietin generation

Research and Practice in Thrombosis and Haemostasis, 2021
Thrombopoietin (TPO), a glycoprotein hormone produced predominantly in the liver, plays important roles in the hematopoietic stem cell (HSC) niche, and is essential for megakaryopoiesis and platelet generation.
Danielle Karakas, Miao Xu, Heyu Ni
doaj   +1 more source

Current gynaecological management of women and girls with bleeding disorders in the United Kingdom: A UKHCDO haemophilia treatment centre survey and evaluation of real‐world clinical practice for the British Journal of Haematology

British Journal of Haematology, Volume 208, Issue 2, Page 661-669, February 2026.
Summary Girls and women with bleeding disorders (GWBD) comprise more than half of all registered patients with bleeding disorders in the UK National Haemophilia Database. The gynaecological care of GWBD, until recently, has not been prioritised despite high health burdens, where four of every five patients experience heavy menstrual bleeding (HMB).
Laura Knox, Imogen Swart‐Rimmer, Naim Rahimi, Callum Harris, Lugain Abdalla, Gary Benson, Clare Brown, Helen Campbell, Ana Carvalhosa, Justin T. Clarke, Sarah Garside, Claire Lentaigne, Jayna Mistry, Priyanka Raheja, Cora Warren, Rezan Abdul‐Kadir, Gill Lowe, Nicola Curry   +17 more
wiley   +1 more source

Subcutaneous Apomorphine Infusion Initiation Is Associated with Impulse Control Disorder Attenuation in Advanced Parkinson's Disease Patients: Insights from the French NS‐Park Cohort

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 142-153, January 2026.
Abstract Background Impulse control disorders (ICD) are common non‐motor complications in Parkinson's disease (PD), particularly in patients receiving oral dopamine agonists (DA). Continuous subcutaneous apomorphine infusion (CSAI) is a device‐aided therapy for advanced PD, but its effects on ICD remain underexplored in real‐world settings.
Clément Desjardins, Paulo André Dias Bastos, Aymeric Lanore, Christine Brefel‐Courbon, Isabelle Benatru, Caroline Giordana, Anne Doe de Maindreville, Giovanni Castelnovo, Philippe Remy, Luc Defebvre, Claire Thiriez, Stéphane Prange, Jean‐Luc Houeto, Alexandra Samier Foubert, Fabienne Ory‐Magne, Raquel Pinhero Barbosa, Nathalie Bertille, Jean‐Christophe Corvol, Olivier Rascol, Margherita Fabbri, on behalf of the NS‐Part Cohort study group, Jean‐Christophe Corvol, Olivier Rascol, Margherita Fabbri, Wassilios Meissner, Stéphane Thobois, Luc Defebvre, Helene Esperou, Florence Tubach, Yann De Rycke, Layidé Roufai, Dalila Ouazib, Sandra Zarrad, Fatma Khelifi, Florence Tubach, Yann De Rycke, Nathalie Bertille, Vanessa Rousseau, Samuel Tessier, Margherita Fabbri, David Tavel, Dounya Metdaoui, Avigaelle Abitbol, Mathias Antunes, Alexis Brice, Suzanne Lesage, Christelle Tessson, Fanny Casse, Mélanie Ferrien, Guillaume Cogan, Lisa Welment, Thierry Moulin, Wassilios Meissner, Claire Thiriez, Stéphane Thobois, Christian Geny, Solène Frismand, Anne‐Gaëlle Corbille, Caroline Giordana, Giovanni Castelnovo, Isabelle Benatru, Sophie Drapier, David Maltete, Christine Tranchant, Olivier Rascol, Mickael Aubignat, Marie Mongin, Matthieu Bereau, Alexandra Foubert‐Samier, Brice Laurens, Sylvain Vergnet, Thomas Boraud, David Bendetowicz, Jade Sarrabere, Dominique Guehl, Pierre Burbaud, Paul‐Alexandre Pfeiffer, Gilles Defer, Bérengère Debilly, Philippe Derost, Alice Dormeuil, Aimée Petit, Alban Gravier, Vincent Schneider, Lucie Garnier, Nicolas Carriere, Olivier Colin, Philippe Couratier, Chloé Laurencin, Stephane Prange, Paul Jaulent, Bruno Plus, Helene Gervais‐Bernard, Alexandre Eusebio, Frédérique Fluchere, Stephan Grimaldi, Valentin Mira, Tatiana Witjas, Mahmoud Charif, Ophelie Forster, Alix Durand, Pauline Prin, Lucie Hopes, Amory Jardel, Salome Puisieux, Guillemette Clement, Philippe Damier, Tiphaine Rouaud, Pascal Derkinderen, Arthur Lionnet, Adrien De Guilhem De Lataillade, Cosmin Alecu, Charlotte Heraud, Marie De Verdal, Graziella Mangone, Sara Sambin, Aymeric Lanore, Thomas Courtin, Louise‐Laure Mariani, Fouad Khoury, Poornima Menon, Florence Cormier‐Dequaire, Emmanuel Flamand‐Roze, David Grabli, Elodie Hainque, Marie Vidhaillet, Aurélie Meneret, Cécile Delorme, Cendrine Foucard, Florian Von Raison, Alexis Elbaz, Andreas Hartmann, Vincent Leclercq, Theodore Soulier, Daniel Torres, Giulia Coarelli, Giorgia Querin, Fabien Hauw, Margaux Dunoyer, Solène Ansquer, Frederique Leh, Marion Leclercq, Simon Lamy, Guillaume Carey, Guillaume Costentin, Clemence Hardy, Mathieu Anheim, Ouhaid Lagha Boukbiza, Thomas Wirth, Jimmy Voirin, Marie Des Neiges Santin, Thomas Bogdan, Margherita Fabbri, Christine Brefel Courbon Ory‐Magne, Clemence Leung, Hélène Catala, Gabrielle Sill, Raquel Pinheiro Barbosa, Lucy Famer, Lucie Braccagni, Hiba Sifaoui, Juliette Palisson, Kenza Benrahmoune Idrissi, Astrid Causel, Lydie Romeo, Constance Bissessur, Audace Cure‐Martin, Charline Compagne, Sandrine Dupouy, Sandrine Villars, Wei‐Ho Lai, Rachida Bari, Damien Chevanne, Elodie Durand, Isabelle Rieu, Stephane Bernard, Corinne Garsault, Nathalie Meunier, Alexia Cresson, Marine Sgard, Marie Dreano, Justine Montillot, Renaud Massart, Pascale Grebent, Pierre Pelissier, Valérie Santraine, Thomas Gaudin, Pierre Boutet, Cécile Thuilier, Coralie Chalot, Céline Prevost, Hélène Videaud, Justine Picut, Christian Tarrade, Catherine Caire, Hélène Merle, Elise Metereau, Mathilde Millot, Chloe Bernardi, Emilie Favre, Adelaide Jaulent, Laura Mundler, Blandine Dufresne, Eve Benchetrit, Valérie Driss, Alexia Arifi, Maura Rodrigues, Lili Le Monnier, Nathalie Dumont, Virginie Bablon, Régis Frenais, Caroline Herve, Christelle Guimber, Vanessa Ferrier, Elodie David, Christina Faroul, Leslie Fra, Elsa Foucaran, Fatima‐Ezzahra Ennaji, Jeremy Bonetto, Ryad Ladghem‐Chikouche, Le Mickael, Sophie Liot, Sonia Messar, Hamza Salah, Amelie Bernardo, Naoual Serari, Emilie Rabois, Carole David, Zoe Fournier, Margaux Bonnaire‐Verdier, Elise Chevaillier, Françoise Kestens, Rozenn Gourhan, Sandra Lopez‐Alfaro, Jean‐François Houvenaghel, Mélanie Alexandre, Christine Bourdonnais, Linda Vernon, Ahmed Boumediene, Hugo Rummel, Céline Julie, Nadine Longato, Célie Phillipps, Anne Claire Andries‐Ros, Stéphanie Bras, Estelle Harroch, Claudia Gillet, Yoan Herades, Eva Camgrand   +249 more
wiley   +1 more source

Eltrombopag for the treatment of inherited thrombocytopenias: a phase II clinical trial

Haematologica, 2020
Patients with inherited thrombocytopenias often require platelet transfusions to raise their platelet count before surgery or other invasive procedures; moreover, subjects with clinically significant spontaneous bleeding may benefit from an enduring ...
Carlo Zaninetti, Paolo Gresele, Antonella Bertomoro, Catherine Klersy, Erica De Candia, Dino Veneri, Serena Barozzi, Tiziana Fierro, Maria Adele Alberelli, Valeria Musella, Patrizia Noris, Fabrizio Fabris, Carlo L. Balduini, Alessandro Pecci   +13 more
doaj   +1 more source

Bernard Soulier Syndrome; A Rare Bleeding Disorder

, 2018
Bleeding syndromes in the newborn are rare, but they may be life-threatening and demand immediate attention. Congenital bleeding disorders especially pose a diagnostic challenge to the clinician because of their rarity and the need to be differentiated ...
Seema Tyagi, Preeti Tripathi, Karthika K. V., H. P. Pati   +3 more
core   +1 more source

ITGA2B/ITGB3‐Related Macrothrombocytopenia Associated With Gain‐of‐Function Mutations in ITGA2B or ITGB3 Genes

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Glanzmann thrombasthenia (GT) is an inherited hemorrhagic disorder characterised by impaired platelet functions, manifested clinically as spontaneous bleeding. It is usually inherited in an autosomal recessive manner. Platelet dysfunction in patients with GT is caused by quantitative and/or qualitative deficiencies in αIIbβ3, which result from
Jiao Wu, Han Yan, Zijian Li, Yilin Zhu, Ruonan Shao, Honglei Xin, Tongyu Jia, Mengyu Ge, Lu Zhang, Suyu Jiang, Jianhua Mao, Jiansong Huang, Chao Fang, Xiaodong Xi, Xiaofeng Shi   +14 more
wiley   +1 more source

Mon‐Pu (Glochidion perakense Hook.f.) as a Promising Novel Natural Source of Antithrombotic and Antioxidant Benefits

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Current evidence suggests that regular consumption of food‐functioned fruits and vegetables could reduce the risk of thrombosis. While some indigenous vegetables from Southern Thailand have been reported to exhibit anticoagulant and antiplatelet activities, their fibrinolytic and thrombolytic properties remain unexplored.
Surachai Techaoei, Muhammad Junaid, Warachate Khobjai, Suriyan Sukati, Anjali Chauhan   +4 more
wiley   +1 more source

Dresden Plate quilt, by Elisa Susanne Long Soulier

, 1935
Image of Dresden Plate quilt created in 1935 by Elisa Susanne Long Soulier. Also includes questionnaires describing the quilt completed by Cora E. Soulier as part of the Utah Quilt Guild\u27s documentation days held from 1988-1994.
Soulier, Elisa Susanne Long
core  

Glanzmann thrombasthenia and Bernard-Soulier syndrome in South Iran

, 2005
Glanzmann thrombasthenia (GT) and Bernard-Soulier syndrome (BSS) are two rare inherited disorders of platelet function. In this study, we report the demographic, clinical and biological characteristics of 2 3 patients with GT and of seven patients with ...
E. Ashouri, P.M. Mannucci, A. Afrabiasi, M. Karimi, A. Artoni, F. Peyvandi   +5 more
core   +1 more source