Results 11 to 20 of about 117,043 (169)

Computational Modeling of the Feasibility of Substituted [1.1.1]Propellane Formation from Anionic Bridgehead Bromide Precursors

open access: yesOrganics, 2023
[1.1.1]Propellane, a compound whose structure includes two saturated carbons in which all four bonds are directed into a single hemisphere, is of theoretical interest, but has also seen recent practical applications.
Katherine E. Gates   +14 more
doaj   +1 more source

Comparison of DNA Extraction and Amplification Techniques for Use with Engorged Hard-Bodied Ticks

open access: yesMicroorganisms, 2022
Tick-borne infections are a serious threat to humans, livestock, and companion animals in many parts of the world, often leading to high morbidity and mortality rates, along with decreased production values and/or costly treatments. The prevalence of the
Gretchen C. Reifenberger   +2 more
doaj   +1 more source

Evaluating Trends in Strangles Outbreaks Using Temperature and Precipitation Data in the United States of America for 2018–2022

open access: yesPathogens, 2023
Strangles is a highly contagious upper respiratory infection of equids that is globally distributed. The causative agent of strangles, Streptococcus equi subspecies equi, can be spread through indirect contact with infected fomites, and studies have ...
Bryce A. Thomas   +3 more
doaj   +1 more source

Cruxome: a powerful tool for annotating, interpreting and reporting genetic variants

open access: yesBMC Genomics, 2021
Background Next-generation sequencing (NGS) is an efficient tool used for identifying pathogenic variants that cause Mendelian disorders. However, the lack of bioinformatics training of researchers makes the interpretation of identified variants a ...
Qingmei Han   +7 more
doaj   +1 more source

Sea Anemones Responding to Sex Hormones, Oxybenzone, and Benzyl Butyl Phthalate: Transcriptional Profiling and in Silico Modelling Provide Clues to Decipher Endocrine Disruption in Cnidarians

open access: yesFrontiers in Genetics, 2022
Endocrine disruption is suspected in cnidarians, but questions remain how occurs. Steroid sex hormones are detected in corals and sea anemones even though these animals do not have estrogen receptors and their repertoire of steroidogenic enzymes appears ...
Michael B. Morgan   +11 more
doaj   +1 more source

1-(4-{[3,5-bis({[3,5-Dimethyl-4-(4-methyl-3,5-dioxo-1,2,4-triazolidin-1-yl)-phenoxy]methyl})phenyl]methoxy}-2,6-dimethyl-phenyl)-4-methyl-1,2,4-triazolidine-3,5-dione

open access: yesMolbank, 2022
Appropriately substituted N-centered urazolyl radicals are capable of generating interesting cage-like structures upon forming N-N bonds. The radicals are generated by the oxidation of the corresponding NH urazole precursors.
Gary W. Breton, James Alexander Bowron
doaj   +1 more source

Exploring the Limits of Reactivity of N-Methyl-1,2,4-triazoline-3,5-dione (MeTAD) with Disubstituted Bicycloalkadienes in the Homo-Diels–Alder Reaction

open access: yesOrganics, 2022
The [2+2+2] cycloaddition (homo-Diels–Alder reaction) of N-substituted 1,2,4-triazoline-3,5-diones (TADs) with bicycloalkadienes produces strained heterocyclic compounds.
Gary W. Breton, Kenneth L. Martin
doaj   +1 more source

Non-invasive plasma testing for CD274 UTR structural variations by next-generation sequencing in cancer

open access: yesCell Death Discovery, 2023
Immunotherapy is now the main choice of systemic therapy for many cancer patients, while current biomarkers for tumor immunotherapy may be limited by the accessibility of patient tumor tissue or tumor neoplastic content.
Wenjuan Zhang   +8 more
doaj   +1 more source

Adapting a Bacterial Unknowns Project to Online Learning: Using Microsoft PowerPoint To Create an Unknowns Identification Simulation

open access: yesJournal of Microbiology & Biology Education, 2021
The COVID-19 pandemic forced institutions to move to online learning abruptly during the spring 2020 semester. As a result of this swift change, many microbiology laboratory courses chose to switch all in-class learning activities to simulations.
DeLacy V. L. Rhodes, Madison R. Barshick
doaj   +1 more source

Differential Expression of Innate and Adaptive Immune Genes during Acute Physical Exercise in American Quarter Horses

open access: yesAnimals, 2023
Overtraining syndrome (OTS) is the reduction in performance due to excess training and lack of proper recovery, which can lead to a chronic deprivation of energy and reduction in the repair of damage that can accumulate over time.
Judith Wilson   +4 more
doaj   +1 more source

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