Results 201 to 210 of about 10,485,189 (358)

Data‐Driven Multi‐Objective Optimization of Large‐Diameter Si Floating‐Zone Crystal Growth

open access: yesAdvanced Theory and Simulations, EarlyView.
This study presents a surrogate‐based Multi‐Objective Optimization framework for Floating Zone silicon crystal growth. An ensemble of Neural Networks is trained on simulation data and combined with Genetic Algorithms to explore trade‐offs in process parameters.
Lucas Vieira   +3 more
wiley   +1 more source

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

open access: yesAdvanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti   +11 more
wiley   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

open access: yesAdvanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance   +17 more
wiley   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

open access: yesAdvanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu   +10 more
wiley   +1 more source

A Hybrid Machine Learning Based Intrusion Detection System for MIL-STD-1553

open access: yesHavacılık ve Uzay Teknolojileri Dergisi
MIL-STD-1553 is a communication standard developed by the US Department of Defense in 1975, primarily utilized in military aircraft, ground vehicles, and spacecraft.
Yunus Emre Çiloğlu, Şerif Bahtiyar
doaj  

BiRNA-BERT allows efficient RNA language modeling with adaptive tokenization. [PDF]

open access: yesCommun Biol
Tahmid MT   +4 more
europepmc   +1 more source

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