Results 61 to 70 of about 8,520 (262)

Biportal Endoscopic Intervention for Lumbar Disk Herniation: Evaluating Clinical Effectiveness and Patient Outcomes [PDF]

open access: yesJournal of Orthopedics and Joint Surgery
Aims and background: Lumbar disk herniation (LDH) affects millions worldwide, spurring advancements in treatment. Biportal endoscopic spinal surgery (BESS) emerges as a promising approach, minimizing invasiveness. BESS employs specialized tools using two
Apoorv Kumar   +3 more
doaj   +1 more source

Discovering Early‐Stage Gas Generation Kinetics Enables Thermal Runaway Early Warning in Lithium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
Operando gas diagnostics reveal a previously unrecognized chemical activation (CA) stage during thermal runaway in lithium‐ion batteries. A physics‐informed gas generation kinetics network (GGKNet) is developed to reconstruct reaction pathways and physical models automatically.
Jiabo Zhang   +6 more
wiley   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

open access: yesAdvanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi   +14 more
wiley   +1 more source

Kaempferol Attenuates Spaceflight‐Associated Knee Cartilage Degradation by Targeting NOX4‐Mediated Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
We have shown that both simulated and actual spaceflight contribute to cartilage degradation in the knees of mice. Using RNA sequencing and bioenergetic profiling, we identified NADPH oxidase 4 (NOX4) as a key factor driving these changes. Additionally, we found that kaempferol, a naturally occurring flavonoid that binds directly to NOX4, reduces ...
Yuesong Yin   +23 more
wiley   +1 more source

Enhancing Performances on Wind Power Fluctuation Mitigation by Optimizing Operation Schedule of Battery Energy Storage Systems With Considerations of Operation Cost

open access: yesIEEE Access, 2019
In this paper, battery energy storage systems (BESSs) are integrated into wind farms (WFs) to mitigate the wind power fluctuations. This paper presents a formulation to optimize the operation schedule of the BESS, with the objective of minimizing the ...
Xinsong Zhang   +3 more
doaj   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

open access: yesAdvanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong   +10 more
wiley   +1 more source

Dispatch strategies for battery energy storage system integrated with utility scale solar system for contingency reserve service: A Malaysian perspective

open access: yesNext Energy
The rapid adoption of solar photovoltaic (PV) systems and battery energy storage systems (BESS) has accelerated the global shift to renewable energy (RE).
Chee Wern Hew   +3 more
doaj   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

open access: yesAdvanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu   +17 more
wiley   +1 more source

Accelerating energy transition through battery energy storage systems deployment: A review on current status, potential and challenges in Malaysia

open access: yesEnergy Strategy Reviews
This paper examines the present status and challenges associated with Battery Energy Storage Systems (BESS) as a promising solution for accelerating energy transition, improving grid stability and reducing the greenhouse gas emissions.
Amani Syafiqah Mohd Razif   +3 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

open access: yes
Arthritis Care &Research, EarlyView.
Catherine Deffendall   +6 more
wiley   +1 more source

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