Results 81 to 90 of about 509,249 (300)
Verifying a dominant cause of output variation
, 2023 Finding the dominant cause(s) of variation in process improvement projects is an important task. Before trying to reduce variation in the dominant cause or mitigate the effect of variation in the dominant cause to reduce output variation, it is strongly ...
Mahsa Panahi (16964917) +2 more
core +2 more sources
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
ERP and best of breed : a comparative analysis
, 2001 Enterprise Resource Planning (ERP) software is the dominant strategic platform for supporting enterprise-wide business processes. However, it has been criticised for being\ud inflexible and not meeting specific organisation and industry requirements.
Holland, Christopher P +5 more
core +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
, 2020 Best Vitelliform Dystrophy or Best disease is an autosomal dominant maculopathy caused by mutations in the BEST1 (or VMD2), which is located on chromosome 11 and encodes the protein bestrophin, this protein localizes to the basolateral plasma membrane of
Wisesaputra, T. A. (Tjok)
core
Frequency dependence of acoustic waves in marine sediments [PDF]
, 2002 In situ techniques provide the most reliable method of examining the geoacoustical properties of marine sediments. In the past, individual in situ surveys have only been able to examine compressional waves over a maximum frequency range of 100 Hz to 50 ...
Robb, G. +7 more
core
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Leading change: an overview of three dominant strategies for change
, 2014 Key learning points Understand three dominant strategies of change. Understand the managerial implications of the strategies. Know when to use the respective strategies.
Schenkel, Andrew,, Andrew Schenkel
core +1 more source
Clinical Ophthalmology, 2020 Mitchell A Jackson,1 Anna M Edmiston,1 Raman Bedi2 1Jacksoneye, Lake Villa, IL, USA; 2IrisARC, Chandigarh, IndiaCorrespondence: Mitchell A JacksonJacksoneye, 300 N Milwaukee Avenue Suite L, Lake Villa, IL 60046, USATel +1-847-356-0700Fax +1-847-356 ...
Jackson MA, Edmiston AM, Bedi R
doaj
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source