Results 61 to 70 of about 2,529,533 (324)
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Magnetic Field Dependent Microwave Losses in Superconducting Niobium Microstrip Resonators
, 2018 We describe an experimental protocol to characterize magnetic field dependent microwave losses in superconducting niobium microstrip resonators. Our approach provides a unified view that covers two well-known magnetic field dependent loss mechanisms ...
Benningshof, Olaf W. B. +10 more
core +1 more source
Impaired Bestrophin Channel Activity in an iPSC-RPE Model of Best Vitelliform Macular Dystrophy (BVMD) from an Early Onset Patient Carrying the P77S Dominant Mutation [PDF]
, 2022 Arnau Navinés‐Ferrer +3 more
openalex +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Fuzzy Subordination Results for Meromorphic Functions Connected with a Linear Operator
Fractal and FractionalThe concept of subordination is expanded in this study from the fuzzy sets theory to the geometry theory of analytic functions with a single complex variable.
Ekram E. Ali +3 more
doaj +1 more source
FORENSIC COMPARISON OF FACIAL IMAGES OF DOPPELGÄNGERS
Теория и практика судебной экспертизы, 2018 The paper examines the problem of forensic examination of doppelgängers' portraits for dominant matching features. The authors outline the types of forensic objectives addressed in the course of such examination, and offer an algorithm for the selection ...
Aleksandr M. Zinin, Zhanna G. Berger
doaj +1 more source
Good Intentions Aren\u27t Enough: Intellectuals and Violence in Luis Goytisolo\u27s \u3cem\u3eMzungo\u3c/em\u3e [PDF]
, 2003 In the 1990s Luis Goytisolo explores the possibilities of popular fiction, adapting various genres (travel, mystery, erotic, historical) to accomodate his long-term project of unpacking Western Values. Indeed, Goytisolo’s flirtation with the best-selling
Carney, Terri
core +1 more source
Statistical Modeling of Epistasis and Linkage Decay using Logic Regression [PDF]
, 2008 Logic regression has been recognized as a tool that can identify and model non-additive genetic interactions using Boolean logic groups. Logic regression, TASSEL-GLM and SAS-GLM were compared for analytical precision using a previously characterized ...
Jean-Luc Jannink +4 more
core +2 more sources
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source