Results 41 to 50 of about 7,710 (298)
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
The Equality Between Linear Transforms of Ordinary Least Squares and Best Linear Unbiased Estimator [PDF]
The best linear unbiased estimator BLUE (CXb) of a linear transform CX b in the general Gauss-Markov model (y, E (y) = X b Cov (y) =a2v) is the linear transform C BLUE (Xb) of the best linear unbiased estimator BLUE (Xb) of Xb. Similarly, for the ordinary least squares estimator OLSE (CXb) = C OLSE (X) .
Groß, Jürgen, Trenkler, Götz
openaire +4 more sources
Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing
ABSTRACT Objective Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly ...
Mirja Thomsen+47 more
wiley +1 more source
GEOGRAPHY MATTERS IN ONLINE HOTEL REVIEWS [PDF]
In resonance with the popularity of user-generated contents (UGC) and the volunteered geographic information (VGI), this study crowdsourced 77,098 hotel reviews of 220 hotels provided by U.S. reviewers in the city of San Francisco, 2002 to 2015.
M. Wang, X. Zhou
doaj +1 more source
Background Large area forest inventories often use regular grids (with a single random start) of sample locations to ensure a uniform sampling intensity across the space of the surveyed populations.
Steen Magnussen+6 more
doaj +1 more source
The Efficiency of Split Panel Designs in an Analysis of Variance Model. [PDF]
We consider split panel design efficiency in analysis of variance models, that is, the determination of the cross-sections series optimal proportion in all samples, to minimize parametric best linear unbiased estimators of linear combination variances ...
Xin Liu, Wei-Guo Wang, Hai-Jun Liu
doaj +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee+6 more
wiley +1 more source
Ordered extreme ranked set sampling and its application in parametric estimation [PDF]
Ranked set sampling (RSS) is applicable whenever ranking of a set of sampling units can be done easily by a judgment method or based on the measurement of an auxiliary variable which can be measured easily.
Manoj Chacko
doaj +1 more source
Herein, a comprehensive framework that enabled the optimization of colloidal solubility within a high‐dimensional parameter space and study of reversible assembly processes is developed. This data‐driven workflow integrated innovations including the robotic platform for automated AuNPs functionalization, machine learning for predicting and revealing ...
Yueyang Gao+5 more
wiley +1 more source
Multifunctional atomic layer deposited coatings and interface treatments enhance direct solar water splitting on GaAs/GaInP tandem cells. Optimized TiO2/Pt nanoparticle bilayers ensure durability and catalytic efficiency with minimal optical losses, while H2 plasma pretreatments maximize photovoltage and interfacial charge extraction.
Tim F. Rieth+8 more
wiley +1 more source