Results 121 to 130 of about 194,005 (326)

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Partition of the genetic trend to validate multiple selection decisions

Animal, 2008
In this note, a procedure to partition the genetic trend of a selected population is presented. Each part of the genetic gain accounts for the Mendelian sampling terms of different groups of animals, which can be sometimes assigned to different selection
L.A. García-Cortés, J.C. Martínez-Ávila, M.A. Toro   +2 more
doaj   +1 more source

Decoding Interfacial Charge‐Carrier Dynamics in Integrated Perovskite/Organic Solar Cells via Numerical Modeling

Advanced Energy Materials, EarlyView.
A physical framework is developed based on drift‐diffusion simulations to elucidate the operation of integrated perovskite/organic solar cells (I‐POSCs) through the lens of interfacial charge‐carrier dynamics. A stepwise analysis establishes key links between carrier transport/recombination phenomena and device performance metrics, offering valuable ...
Jingjing Tian, Chao Liu, Karen Forberich, Rong Wang, Larry Lüer, Christoph J. Brabec   +5 more
wiley   +1 more source

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

Angewandte Chemie, EarlyView.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg, Yurii Dubanych, Spyridon Kosteletos, Taoran Xiao, Martin Neuenschwander, Tillmann Utesch, Michael Lisurek, Carl Öster, Andreas Oder, Carola Seyffarth, Kathrin Bach, Denise‐Liù Gracias Leone, František Filandr, Marc Wegert, Sascha Lange, Henry Sawczyc, Jens Peter von Kries, Christian P. R. Hackenberger, Edgar Specker, Han Sun, Kvido Stříšovský, Adam Lange   +21 more
wiley   +2 more sources

Analysis of Optimal Prediction Under Stochastically Restricted Linear Model and Its Subsample Models

Axioms
This paper provides a study on optimal prediction problems in a linear model and its subsample models with linear stochastic restrictions, using matrix theory for precise analytical solutions.
Nesrin Güler
doaj   +1 more source

Comparison of test-day and lactation models of sire evaluation in Murrah buffalo

Indian Journal of Animal Sciences, 2014
The aim of the study was to investigate efficiency of test-day model (TDM) compared to lactation model (LM) for genetic evaluation of Murrah buffalo bulls.
VIJAY KUMAR, A K CHAKRAVARTY, C S PATIL, JAMUNA VALSALAN, ATUL MAHAJAN, PUSHP RAJ SHIVAHRE   +5 more
doaj   +1 more source

AIC, Cp and estimators of loss for elliptically symmetric distributions

, 2013
In this article, we develop a modern perspective on Akaike's Information Criterion and Mallows' Cp for model selection. Despite the diff erences in their respective motivation, they are equivalent in the special case of Gaussian linear regression.
Boisbunon, Aurélie, Canu, Stephane, Fourdrinier, Dominique, Strawderman, William, Wells, Martin T.   +4 more
core   +1 more source

Application of Spatial Empirical Best Linear Unbiased Prediction (SEBLUP) of Open Unemployment Rate on Sub-District Level Estimation in Banten Province

, 2022
Apriliansyah Apriliansyah, Ika Yuni Wulansari   +1 more
openalex   +2 more sources

Do outgrower schemes enhance technology adoption and productivity? Evidence from maize farmers in Northern Ghana

Agribusiness, EarlyView.
Abstract Nucleus outgrower schemes are contractual arrangements where well‐resourced large‐scale farmers (nucleus farmers) are empowered by development support agencies to take charge of smallholder farmers, by providing them with market access and the necessary training on agronomic practices and farm inputs for production.
Dominic Tasila Konja, Awudu Abdulai
wiley   +1 more source

Analyzing individual rent price ratios in eastern German agricultural land markets: A GAMLSS approach

Agribusiness, EarlyView.
Abstract This study explores the rent price ratio in agricultural land markets, crucial for evaluating market efficiency, policy needs, and farmer decision‐making. Traditionally, the analyses faced challenges due to the absence of concurrent sale and rent data for the same land, potentially leading to biased results.
Marius Michels, Cord‐Friedrich von Hobe, Miryam Sarah Merk, Thomas Kneib, Oliver Musshoff   +4 more
wiley   +1 more source