Results 181 to 190 of about 194,005 (326)
ChemMedChem, EarlyView.This study uses six small‐molecule inhibitors to evaluate optimal cellular accumulation assay conditions in a 96‐well format with high performance liquid chromatography with tandem mass spectrometry detection. The obtained medium to high‐throughput workflow is suitable for reliably identifying cellular accumulation, valuable for preclinical selection ...
Alina Metzen, Katharina Rox
wiley +1 more source
Is it reasonable to use of a kinship matrix for best linear unbiased prediction? [PDF]
, 2019 Bongsong Kim
openalex +1 more source
Addressing Causality and Homogeneity Assumptions in Exposure‐Response Analyses
Clinical Pharmacology &Therapeutics, EarlyView.Exposure‐response, or pharmacokinetic–pharmacodynamic (PKPD), analyses support many drug development decisions. It is typically applied without assessment of causality and homogeneity, where the latter refers to the assumption that the reason for variability in exposure is unimportant for the impact on response.
Mats O. Karlsson, Divya Brundavanam
wiley +1 more source
Enhanced Reliability of the Evaluation of Fertility Traits in Pura Raza Española Horses Using Single-Step Genomic Best Linear Unbiased Prediction. [PDF]
Genes (Basel)Ziadi C +6 more
europepmc +1 more source
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT Using the environmental quality cost management model, this study examines how fraud risk management (FRM) influences corporate sustainability performance (CSP) and how ownership structures moderate it. The study uses artificial neural networks (ANN) and logistic regression models to test two hypotheses. H1 demonstrates that the prevention and
Israel Akinbode Owolabi +3 more
wiley +1 more source
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT This study explores the potential influence of key components of the board of directors' architecture on ESG outcomes. Specifically, we focus on the effects of demographic components (gender and cultural diversity), structural and compositional factors (size, CEO‐Chair separation, and the presence of independent/non‐executive directors), and ...
Jorge Ochaita‐Gonzalez +3 more
wiley +1 more source
Methods of Calculating Prediction Error Variance and Prediction Accuracy for Restricted Best Linear Unbiased Prediction of Breeding Values. [PDF]
J Anim Breed GenetSatoh M.
europepmc +1 more source
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT This paper presents a systematic literature review exploring the intersection of Green Human Resource Management (GHRM) and Environmental, Social, and Governance (ESG) criteria. The study synthesizes current research, identifies prevailing trends, and highlights gaps within this emerging field.
Zile Huma +3 more
wiley +1 more source
Performance Comparison of Genomic Best Linear Unbiased Prediction and Four Machine Learning Models for Estimating Genomic Breeding Values in Working Dogs. [PDF]
Animals (Basel)Thorsrud JA +4 more
europepmc +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Previous research has revealed negative effects of appearance‐related social media content, such as fitspiration, on body satisfaction. However, specific interventions to reduce these detrimental effects are scarce. Therefore, this randomized controlled pilot trial investigated the efficacy of the four‐week online intervention body ...
Gritt Ladwig +4 more
wiley +1 more source