STIP1 drives Metabolic Reprogramming in Esophageal Squamous Cell Carcinoma via AHCY‐LDHA Axis
Exploration, EarlyView.A schematic model illustrating that LCA can inhibit ESCC growth by inhibiting the STIP1/AHCY/LDHA axis. In brief. Jin et al. demonstrated that targeting STIP1 can significantly inhibit the progression of esophageal squamous cell carcinoma. The high expression of STIP1 increased the interaction between AHCY and LDHA and then AHCY recruits PRMT3 to ...
Guoguo Jin +16 more
wiley +1 more source
The best linear unbiased prediction (BLUP) method as a tool to estimate the lifetime risk of pancreatic ductal adenocarcinoma in high-risk individuals with no known pathogenic germline variants. [PDF]
Fam CancerCristina-Marianini-Rios +18 more
europepmc +1 more source
CORRELATION STUDIES ON SIRE BEST LINEAR UNBIASED PREDICTION VALUES AND RANKS OF MEHALLAH 85 TURKEY PERTAINING BODY WEIGHT AND CONFORMATION MEASURES [PDF]
, 2002 Mohamed E. Mostafa
openalex +1 more source
Exploration, EarlyView.Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu +5 more
wiley +1 more source
A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection
Food Frontiers, EarlyView.ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah +1 more
wiley +1 more source
Comparison of multiple-trait genetic evaluation accuracy using region marker relationships with traditional best linear unbiased prediction (BLUP) [PDF]
, 2010 Mahboubeh +6 more
openalex +1 more source
Advanced Genetics, EarlyView.Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li +13 more
wiley +1 more source
Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges
Advanced Genetics, EarlyView.This review provides a comprehensive comparison of RNA‐ and protein‐centric methodologies for investigating RNA–protein interactions, emphasizing their respective advantages, limitations, and suitable applications. It highlights recent technological innovations, outlines strategic method selection criteria, and addresses key challenges.
Wenkai Yi, Jian Yan
wiley +1 more source
Global Strategy Journal, EarlyView.Abstract Research Summary We extend the property rights theory to show that stronger ownership control incentivizes owners to push for communalizing private environmental costs unless counterbalancing internal and external governance mechanisms are prevalent. Using a sample of 16,286 observations for 3275 firms across 43 countries between 2008 and 2017,
Punit Arora, Tanusree Jain, Ajai Gaur
wiley +1 more source