Results 61 to 70 of about 179,787 (326)

AMMI Model for Yield Estimation in Multi-Environment Trials: A Comparison to BLUP [PDF]

, 2016
Maximum information from the Multi-environment trials (MET) can be reached by seeking the best estimator of each genotype's mean yield in a given environment.
Hadi, Alfian Futuhul, Sa’diyah, Halimatus   +1 more
core   +1 more source

Genome-wide Association Study (GWAS) and Its Application for Improving the Genomic Estimated Breeding Values (GEBV) of the Berkshire Pork Quality Traits [PDF]

Asian-Australasian Journal of Animal Sciences, 2015
The missing heritability has been a major problem in the analysis of best linear unbiased prediction (BLUP). We introduced the traditional genome-wide association study (GWAS) into the BLUP to improve the heritability estimation.
Young-Sup Lee, Hyeonsoo Jeong, Mengistie Taye, Hyeon Jeong Kim, Sojeong Ka, Youn-Chul Ryu, Seoae Cho   +6 more
doaj   +1 more source

Predictive ability of genome-assisted statistical models under various forms of gene action [PDF]

, 2018
Recent work has suggested that the performance of prediction models for complex traits may depend on the architecture of the target traits. Here we compared several prediction models with respect to their ability of predicting phenotypes under various ...
Gianola, Daniel, Kranis, Andreas, Mehrgardi, Ahmad Ayatollahi, Momen, Mehdi, Morota, Gota, Rosa, Guilherme J M, Sheikhi, Ayyub, Tusell, Llibertat   +7 more
core   +4 more sources

Plasma microRNA Signature as Predictive Marker of Clinical Response to Therapy During Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone, Alessandra Colamatteo, Teresa Micillo, Gianmarco Abbadessa, Silvia Garavelli, Clorinda Fusco, Claudia Russo, Francesco Perna, Federica Garziano, Claudia La Rocca, Maria Mottola, Giorgia Teresa Maniscalco, Simona Bonavita, Antonio Luca Spiezia, Alessia Castiello, Roberta Lanzillo, Vincenzo Brescia Morra, Claudio Procaccini, Paola de Candia, Giuseppe Matarese   +19 more
wiley   +1 more source

Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly ...
Mirja Thomsen, Fabian Ott, Sebastian Loens, Gamze Kilic‐Berkmen, Ai Huey Tan, Shen‐Yang Lim, Ebba Lohmann, Kaja M. Schröder, Lea Ipsen, Lena A. Nothacker, Linn Welzel, Alexandra S. Rudnik, Frauke Hinrichs, Thorsten Odorfer, Kirsten E. Zeuner, Friederike Schumann, Andrea A. Kühn, Simone Zittel, Marius Moeller, Robert Pfister, Christoph Kamm, Anthony E. Lang, Yi Wen Tay, Ana Luísa de Almeida Marcelino, Marie Vidailhet, Emmanuel Roze, Joel S. Perlmutter, Jeanne S. Feuerstein, Victor S. C. Fung, Florence Chang, Richard L. Barbano, Steven Bellows, Aparna A. Wagle Shukla, Alberto J. Espay, Mark S. LeDoux, Brian D. Berman, Stephen Reich, Andres Deik, Andre Franke, Michael Wittig, Sören Franzenburg, Jens Volkmann, Norbert Brüggemann, H. A. Jinnah, Tobias Bäumer, Christine Klein, Hauke Busch, Katja Lohmann   +47 more
wiley   +1 more source

Parametric Transformed Fay-Herriot Model for Small Area Estimation [PDF]

, 2014
In this paper, we consider parametric transformed Fay-Herriot models, and clarify conditions on transformations under which the estimator of the transformation is consistent. It is shown that the dual power transformation satisfies the conditions.
Kubokawa, Tatsuya, Sugasawa, Shonosuke
core   +1 more source

On the Lindley Record Values and Associated Inference

Journal of Statistical Theory and Applications (JSTA), 2018
In this paper, we discuss the record values arising from the Lindley distribution. We compute the means, variances and covariances of the record values.
A. Fallah, A. Asgharzadeh, S.M.T.K. MirMostafaee   +2 more
doaj   +1 more source

Domestic and Interbull information in the single step genomic evaluation of Holstein milk production

Czech Journal of Animal Science, 2014
Estimated breeding values and genomic enhanced breeding values for milk production of young genotyped Holstein bulls were predicted using a conventional animal model, ridge regression genomic prediction procedure, genomic best linear unbiased prediction,
J. Přibyl, J. Bauer, P. Pešek, J. Přibylová, L. Vostrý, L. Zavadilová   +5 more
doaj   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source

Comparison of Univariate and Multivariate Applications of GBLUP and Artificial Neural Network for Genomic Prediction of Growth and Carcass Traits in the Brangus Heifer Population

Ruminants
Data for growth (birth, weaning and yearling weights) and carcass (longissimus muscle area, intramuscular fat percentage and depth of rib fat) traits and 50K SNP marker data to calculate the genomic relationship matrix were collected from 738 Brangus ...
Sunday O. Peters, Kadir Kızılkaya, Mahmut Sinecen, Milt G. Thomas   +3 more
doaj   +1 more source