Results 201 to 210 of about 416,993 (285)

THE BEST PROXIMITY PAIR FOCUSING ON MONOTONICITY AND T-ABSOLUTELY DIRECT SETS

, 2020
Ali Asghar Sarvari, H. Mazaheri, H. R. Khademzadeh   +2 more
openalex   +2 more sources

Split-APEX implicates splicing factor SRSF1 and splicing helicases in ribosomal biogenesis. [PDF]

Front Mol Biosci
Paschalis V, Wills MFK, De Gusmao Araujo P, Lucas C, Tubasum S, Cui S, Kara H, Bueno-Alejo C, Santana-Vega M, Taladriz-Sender A, Zhao Z, Axer A, Dominguez C, Clark AW, Burley GA, Hudson AJ, Eperon IC.   +16 more
europepmc   +1 more source

Using Bayesian Optimization to Increase the Efficiency of III‐V Multijunction Solar Cells

Advanced Theory and Simulations, EarlyView.
Technology Computer Aided Design (TCAD) modeling is crucial for designing complex optoelectronic devices like III‐V multijunction solar cells. Bayesian optimization is proposed as a robust method to address challenges in optimizing costly black‐box TCAD solvers.
Pablo F. Palacios, Carlos Algora
wiley   +1 more source

Unified representation and scoring framework for anomaly detection in attributed networks with emphasis on structural consistency and attribute integrity. [PDF]

Sci Rep
Khan W, Ebrahim N, Alsaadi M, Elloumi M.
europepmc   +1 more source

First‐Principles Structure–Activity Relationship Insights Into Phenolic Scaffolds: QSAR Modeling and Drug‐Likeness Screening

Advanced Theory and Simulations, EarlyView.
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer, Sridhar Priyankha, Gopal Hema, Anouar Zerouali, Hamza Haddag, Muneerah Mogren Al Mogren, Muthuramalingam Prakash, Majdi Hochlaf   +7 more
wiley   +1 more source

Fluorescent modifications in aptamer switches-positional, structural, and neighboring pair effects on sensor performance. [PDF]

Nucleic Acids Res
Li AZ, Belzberg CHT, Sidhu M, Hariri AA.
europepmc   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways. [PDF]

Adv Sci (Weinh)
Buck A, Dupont T, Andrews Cavanagh R, Postal O, Bourien J, Puel JL, Michalski N, Gourévitch B.   +7 more
europepmc   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source