Results 61 to 70 of about 4,213,432 (261)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Non-convex proximal pair and relatively nonexpansive maps with respect to orbits
Journal of Inequalities and Applications, 2021 Every non-convex pair ( C , D ) $(C, D)$ may not have proximal normal structure even in a Hilbert space. In this article, we use cyclic relatively nonexpansive maps with respect to orbits to show the presence of best proximity points in C ∪ D $C\cup D$ ,
Laishram Shanjit, Yumnam Rohen
doaj +1 more source
Best proximity point theorems for cyclic p-contractions with some consequences and applications
Nonlinear Analysis, 2021 In this paper, we introduce the concept of cyclic p-contraction pair for single-valued mappings. Then we present some best proximity point results for such mappings defined on proximally complete pair of subsets of a metric space.
Mustafa Aslantas +2 more
doaj +1 more source
A Common Best Proximity Point Theorem for Ï•-dominated Pair
European Journal of Pure and Applied Mathematics, 2018 In the present research, an interesting common best proximity point theorem for pairs of non-self-mappings is presented. It satises a weakly contraction-like condition, thereby producing common optimal approximate solutions of certain simultaneous xed point equations.
Iranmanesh, Mahdi +1 more
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Some Results on Iterative Proximal Convergence and Chebyshev Center
Journal of Function Spaces, 2021 In this paper, we prove a sufficient condition that every nonempty closed convex bounded pair M,N in a reflexive Banach space B satisfying Opial’s condition has proximal normal structure.
Laishram Shanjit +3 more
doaj +1 more source
Existence of equilibrium pair in best proximity settings
Applied Mathematical Sciences, 2015 In this paper, using a best proximity theorem, we will prove a basic existence theorem of equilibrium pair for a free 1-person game which generalizes both xed point theorems and equilibrium existence theorems in best proximity settings.
openaire +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source