Current Challenges of Transcription Compartmentalization Research
Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley +1 more source
A modular framework for automated segmentation and analysis of AFM imaging of chromatin organization. [PDF]
Sørensen EW +22 more
europepmc +1 more source
Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li +8 more
wiley +1 more source
CRM-TI: an enhanced pipeline for computationally assigning the target genes of cis-regulatory modules by considering comprehensive long-range regulation mechanisms. [PDF]
Yu YH, He GL, Yang TH.
europepmc +1 more source
Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen +5 more
wiley +1 more source
Treatment of hepatic hemangiomas in the era of laparoscopic surgery: Enucleation versus hepatectomy. [PDF]
Jiang B +5 more
europepmc +1 more source
Praxeological analysis (PA/CPA) for stigma, health inequalities, and coercion in women's services. [PDF]
Hutchinson P, Chikwira L.
europepmc +1 more source
Modeling the impact of climate variables on agriculture through the F-transform. [PDF]
Amicizia B +4 more
europepmc +1 more source
Reconstructing 3D transcriptional organization from spatial transcriptomics reveals consistent oncogenic translocations and developmental dynamics. [PDF]
Sheng Y +5 more
europepmc +1 more source

