Results 51 to 60 of about 4,206,969 (256)
When Should Recommenders Account for Low QoS?
IEEE Access, 2023 Content recommendation systems, also known as recommenders, are pervasive and have significant impact on user demands over the Internet. Platforms such as YouTube and Netflix constantly seek to improve their recommendation systems, to provide better ...
Mateus Schulz Nogueira +5 more
doaj +1 more source
Cyclic contractions and best proximity pair theorems
, 2010 This paper has been ...
Kosuru, G. Sankara Raju, Veeramani, P.
openaire +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FilomatIn the setup of metric spaces, many recent studies established a significant variety of control type mappings and illustrated some fixed point results. To represent various contractivity conditions, Khojasteh et al. have established the idea of a simulation function and came up with certain conclusions about the fixed point. For two nonlinear operators
P PaunovicMarija +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
A Common Best Proximity Point Theorem for Ï•-dominated Pair
European Journal of Pure and Applied Mathematics, 2018 In the present research, an interesting common best proximity point theorem for pairs of non-self-mappings is presented. It satises a weakly contraction-like condition, thereby producing common optimal approximate solutions of certain simultaneous xed point equations.
Iranmanesh, Mahdi +1 more
openaire +2 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Best Proximity Pair Results for Relatively Nonexpansive Mappings in Geodesic Spaces [PDF]
Numerical Functional Analysis and Optimization, 2014 Given $A$ and $B$ two nonempty subsets in a metric space, a mapping $T : A \cup B \rightarrow A \cup B$ is relatively nonexpansive if $d(Tx,Ty) \leq d(x,y) \text{for every} x\in A, y\in B.$ A best proximity point for such a mapping is a point $x \in A \cup B$ such that $d(x,Tx)=\text{dist}(A,B)$.
Fernández León, Aurora +1 more
openaire +4 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source