Results 91 to 100 of about 8,011,019 (282)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Best Proximity Point Results in Non-Archimedean Modular Metric Space

Mathematics, 2017
In this paper, we introduce the new notion of Suzuki-type ( α , β , θ , γ ) -contractive mapping and investigate the existence and uniqueness of the best proximity point for such mappings in non-Archimedean modular metric space using the weak ...
Mohadeshe Paknazar, Manuel De la Sen
doaj   +1 more source

Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos, Morgan C. Devore, Christina Lam, Courtney Park, Sanjay Bidichandani, David R. Lynch   +5 more
wiley   +1 more source

Proximity-based non-contact perception and omnidirectional point-cloud generation based on hierarchical information on fingertip proximity sensors

, 2021
In this study, we examine robotic proximity perception for both reactive control and 3D point-cloud acquisition using a multi-fingered robot hand. A reactive controller adjusts the relative position and orientation between the fingertips and the target ...
Y. Suzuki (2918900)
core   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Best Proximity Point of Generalized θ-φ-Proximal Non-self Contractions

European Journal of Mathematical Analysis
In this manuscript, motivated and inspired by results of Best proximity point of generalized F -proximal non-self contractions, we introduce the concept of generalized θ-φ-proximal contraction and prove new best proximity results for these contractions ...
Mohamed Rossafi, Abdelkarim Kari
doaj   +1 more source

Best proximity version of Krasnoselskii’s fixed point theorem

, 2020
We prove a best proximity point version of Krasnoselskii’s fixed point theorem. As a consequence we obtain the existence of best proximity points of relatively u-continuous maps for a pair of compact convex ...
Veeramani P., Kar S.
core  

Biopsychosocial Determinants of Hand Function and Its Trajectories Over Five Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

Best proximity point and best proximity coupled point in a complete metric space with (P)-property

Filomat, 2015
In this paper, we utilize the concept of (P)-property, weak (P)-property and the comparison function to introduce and prove an existence and uniqueness theorem of a best proximity point. Also, we introduce the notion of a best proximity coupled point of a mapping F: X x X ? X.
Wasfi Shatanawi, Ariana Pitea
openaire   +2 more sources