Results 71 to 80 of about 8,286,670 (284)

Best proximity points for proximal contractions

open access: yes, 2012
In this paper we improve and extend some best proximity point results concerning the so-called proximal contractions. Specifically, compactness assumptions under the sets A and B are removed to consider completeness conditions instead.
openaire   +4 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Best proximity points and fixed points for p-summing maps [PDF]

open access: yesFixed Point Theory and Applications, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Petric, Mihaela, Zlatanov, Boyan
openaire   +1 more source

Best proximity version of Krasnoselskii's fixed point theorem

open access: yes, 2020
We prove a best proximity point version of Krasnoselskii’s fixed point theorem. As a consequence we obtain the existence of best proximity points of relatively u-continuous maps for a pair of compact convex ...
Veeramani P., Kar S.
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

KKM-type theorems for best proximity points

open access: yesApplied Mathematics Letters, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
V. Sankar Raj, S. Somasundaram
openaire   +3 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Best proximity points revisited

open access: yesFilomat, 2019
In this paper, using the concept of w-distance on a metric space, we prove some new best proximity point results for the mappings of Meir-Keeler type. As an application, we derive some recent best proximity point results of the aforementioned type.
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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