Results 61 to 70 of about 8,286,670 (284)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Existence of coupled coincidence best proximity point [PDF]
Surveys in Mathematics and its ApplicationsThis work of optimality is engaged with couple coincidence best proximity point. We have developed some optimal results where control functions and non-linear weak inequalities are evident. Further using our results, we establish some fixed point results.
Pulak Konar, Sumit Chandok
doaj
Best Proximity Pairs Theorems for Continuous Set-Valued Maps
, 2008 A best proximity pair for a set-valued map F:A⊸B with respect to a set-valued map G:A⊸A is defined, and a new existence theorem of best proximity pairs for continuous set-valued maps is proved in nonexpansive retract metric spaces.
A. P. Farajzadeh +12 more
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Best Proximity Point Results on Strong b-Metric Spaces
Journal of New Theory, 2021 In the present paper, we prove the two best proximity point results on strong b-metric spaces with coefficient λ by introducing two new concepts which are named as BW b-contraction and proximal BW b-contraction.
Mustafa Aslantaş
doaj
On Best Proximity Points in Metric and Banach Spaces [PDF]
Canadian Journal of Mathematics, 2011 Abstract In this paper we study the existence and uniqueness of best proximity points of cyclic contractions as well as the convergence of iterates to such proximity points. We take two different approaches, each one leading to different results that complete, if not improve, other similar results in the theory.
Espínola García, Rafael +1 more
openaire +4 more sources
Common best proximity point theorems for certain types of mappings
summary:Let $S$ and $T$ be two single-valued non-self-mappings from a nonempty set $\mathcal {P}$ to another nonempty set $\mathcal {Q}$. As they are non-self-mappings, the equations $Sx=x$ and $Tx=x$ do not have a common solution.
Murali, Arunachalam +1 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source