Results 51 to 60 of about 173,800 (258)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Best proximity points in ℱ-metric spaces with applications

open access: yesDemonstratio Mathematica, 2023
The aim of this article is to introduce α\alpha -ψ\psi -proximal contraction in the setting of ℱ-metric space and prove the existence of best proximity points for these contractions.
Lateef Durdana
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Existence of coupled coincidence best proximity point [PDF]

open access: yesSurveys in Mathematics and its Applications
This work of optimality is engaged with couple coincidence best proximity point. We have developed some optimal results where control functions and non-linear weak inequalities are evident. Further using our results, we establish some fixed point results.
Pulak Konar, Sumit Chandok
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Best Proximity Point and Geometric Contraction Maps

open access: yesJournal of Mathematical Extension, 2014
In this paper we introduce geometric contraction map and give a new condition for the existence and uniqueness of best proximity point of geometric contractions.
M. R. Haddadi
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Best proximity points for proximal contractions

open access: yes, 2012
In this paper we improve and extend some best proximity point results concerning the so-called proximal contractions. Specifically, compactness assumptions under the sets A and B are removed to consider completeness conditions instead.
openaire   +4 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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