Results 51 to 60 of about 8,286,670 (284)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On the existence of coupled best proximity point and best proximity point for Suzuki type alpha^+-theta-proximal multivalued mappings

The Journal of Nonlinear Sciences and Applications, 2017
Summary: Following the study for the best proximity points of the Suzuki type \(\alpha^+\)-\(\theta\)-proximal single-valued mappings given by \textit{N. Hussain} et al. [Fixed Point Theory Appl. 2016, Paper No. 14, 20 p. (2016; Zbl 1347.54085)], we deal with the Suzuki type \(\alpha^+\)-\(\theta\)-proximal multivalued mappings satisfying generalized ...
Liu, Haiming, Fan, Xiaoming, Yan, Lixu, Wang, Zhigang   +3 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Results on the Existence and Convergence of Best Proximity Points [PDF]

Fixed Point Theory and Applications, 2010
AbstractWe first consider a cyclic "Equation missing"-contraction map on a reflexive Banach space "Equation missing" and provide a positive answer to a question raised by Al-Thagafi and Shahzad on the existence of best proximity points for cyclic "Equation missing"-contraction maps in reflexive Banach spaces in one of their works (2009).
Ali Abkar, Moosa Gabeleh
openaire   +4 more sources

φ-Best proximity point theorems and applications to variational inequality problems

, 2017
The main concern of this study is to introduce the notion of φ-best proximity points and establish the existence and uniqueness of φ-best proximity point for non-self mappings satisfying (F,φ)-proximal and (F,φ)-weak proximal contraction conditions in ...
Isik, Huseyin, Vetro, C., Işık, H., Hüseyin Işık, Calogero Vetro, Isik, Huseyn, Vetro, Calogero, Sezen, M. Sangurlu, M. Sangurlu Sezen, Sezen, M.S., Sezen, MÜZEYYEN   +10 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Best proximity point results with their consequences and applications

Journal of Inequalities and Applications, 2022
In the commenced work, we establish some best proximity point results for multivalued generalized contractions on partially ordered complete metric spaces along with the tactic of altering distance function.
Satyendra Kumar Jain, Gopal Meena, Deepak Singh, Jitendra Kumar Maitra   +3 more
doaj   +1 more source

A discussion on best proximity point and coupled best proximity point in partially ordered metric spaces [PDF]

Fixed Point Theory and Applications, 2015
AbstractIn this paper we establish some best proximity point results using generalized weak contractions with discontinuous control functions. The theorems are established in metric spaces with a partial order. We view the main problem in the paper as a problem of finding an optimal approximate solution of a fixed point equation.
Choudhury, Binayak S, Metiya, Nikhilesh, Postolache, Mihai, Konar, Pulak   +3 more
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Existence of fixed point and best proximity point of p-cyclic orbital phi-contraction map

Nonlinear Analysis, 2022
In this manuscript, p-cyclic orbital ϕ-contraction map over closed, nonempty, convex subsets of a uniformly convex Banach space X possesses a unique best proximity point if the auxiliary function ϕ is strictly increasing.
Prabavathy Magadevan, Saravanan Karpagam, Erdal Karapınar   +2 more
doaj   +1 more source