Results 41 to 50 of about 173,800 (258)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Best proximity point results with their consequences and applications
Journal of Inequalities and Applications, 2022 In the commenced work, we establish some best proximity point results for multivalued generalized contractions on partially ordered complete metric spaces along with the tactic of altering distance function.
Satyendra Kumar Jain +3 more
doaj +1 more source
Existence of fixed point and best proximity point of p-cyclic orbital phi-contraction map
Nonlinear Analysis, 2022 In this manuscript, p-cyclic orbital ϕ-contraction map over closed, nonempty, convex subsets of a uniformly convex Banach space X possesses a unique best proximity point if the auxiliary function ϕ is strictly increasing.
Prabavathy Magadevan +2 more
doaj +1 more source
The Journal of Nonlinear Sciences and Applications, 2017 Summary: Following the study for the best proximity points of the Suzuki type \(\alpha^+\)-\(\theta\)-proximal single-valued mappings given by \textit{N. Hussain} et al. [Fixed Point Theory Appl. 2016, Paper No. 14, 20 p. (2016; Zbl 1347.54085)], we deal with the Suzuki type \(\alpha^+\)-\(\theta\)-proximal multivalued mappings satisfying generalized ...
Liu, Haiming +3 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Best proximity points of cyclic mappings
Applied Mathematics Letters, 2012 Let \(A\) and \(B\) be nonempty closed subsets of a complete metric space \((X,d)\). A map \(T: A \cup B \rightarrow A \cup B\) is called cyclic if \(T(A) \subset B\) and \(T(B) \subset A\). A point \(x \in A \cup B\) is called a best proximity point for \(T\) if \(d(x,T(x))\) coincides with the infimum of the set \(\{ d(a,b) : a \in A,\, b \in B \}\).
openaire +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
On Best Proximity Points in Metric and Banach Spaces [PDF]
Canadian Journal of Mathematics, 2011 Abstract In this paper we study the existence and uniqueness of best proximity points of cyclic contractions as well as the convergence of iterates to such proximity points. We take two different approaches, each one leading to different results that complete, if not improve, other similar results in the theory.
Espínola García, Rafael +1 more
openaire +4 more sources