Results 71 to 80 of about 916,486 (287)

Transparent and scalable client-side server selection using netlets [PDF]

, 2003
Replication of web content in the Internet has been found to improve service response time, performance and reliability offered by web services. When working with such distributed server systems, the location of servers with respect to client nodes is ...
Collier, Martin, Dharmalingam, Kalaiarul
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Best proximity points for p-summing cyclic orbital Meir–Keeler contractions

Nonlinear Analysis, 2015
We generalize the cyclic orbital Meir–Keeler contractions, which were introduced by S. Karpagam and S. Agrawal in the context of p-summing maps. We found sufficient conditions for these new type of maps, that ensure the existence and uniqueness of fixed ...
Boyan Zlatanov
doaj   +1 more source

Best proximity points for proximal contractions

, 2012
In this paper we improve and extend some best proximity point results concerning the so-called proximal contractions. Specifically, compactness assumptions under the sets A and B are removed to consider completeness conditions instead.
openaire   +4 more sources

Generalization of simulation functions for finding best proximity pair, best proximity point and best proximity coincidence point

Filomat
In the setup of metric spaces, many recent studies established a significant variety of control type mappings and illustrated some fixed point results. To represent various contractivity conditions, Khojasteh et al. have established the idea of a simulation function and came up with certain conclusions about the fixed point. For two nonlinear operators
P PaunovicMarija, Mohammad Haddadi, Vahid Parvaneh   +2 more
openaire   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Random Best Proximity Points for α-Admissible Mappings via Simulation Functions

Mathematics, 2018
In this paper, we introduce a new concept of random α -proximal admissible and random α - Z -contraction. Then we establish random best proximity point theorems for such mapping in complete separable metric spaces.
Chayut Kongban, Poom Kumam, Juan Martínez-Moreno   +2 more
doaj   +1 more source

Recurrent oligomers in proteins - an optimal scheme reconciling accurate and concise backbone representations in automated folding and design studies

, 2000
A novel scheme is introduced to capture the spatial correlations of consecutive amino acids in naturally occurring proteins. This knowledge-based strategy is able to carry out optimally automated subdivisions of protein fragments into classes of ...
Maritan, Amos, Micheletti, Cristian, Seno, Flavio   +2 more
core   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source