Results 81 to 90 of about 5,989,700 (306)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Best proximity points for p-summing cyclic orbital Meir–Keeler contractions
Nonlinear Analysis, 2015 We generalize the cyclic orbital Meir–Keeler contractions, which were introduced by S. Karpagam and S. Agrawal in the context of p-summing maps. We found sufficient conditions for these new type of maps, that ensure the existence and uniqueness of fixed ...
Boyan Zlatanov
doaj +1 more source
Best proximity points for proximal contractions
, 2012 In this paper we improve and extend some best proximity point results concerning the so-called proximal contractions. Specifically, compactness assumptions under the sets A and B are removed to consider completeness conditions instead.
openaire +4 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
On existence and uniqueness of best proximity points for proximal β-quasi contractive mappings on metric spaces [PDF]
, 2021 This paper focus on the study of the generalization of the best proximity point theorems for non-self contractions. In fact we propose two new theorems on the existence and the uniqueness of best proximity points for proximal β-quasi contractive ...
Jatradat, M. M.M. +2 more
core +2 more sources
Random Best Proximity Points for α-Admissible Mappings via Simulation Functions
Mathematics, 2018 In this paper, we introduce a new concept of random α -proximal admissible and random α - Z -contraction. Then we establish random best proximity point theorems for such mapping in complete separable metric spaces.
Chayut Kongban +2 more
doaj +1 more source
AIMS MathematicsWe introduce a large class of mappings called proximal Górnicki mappings in metric spaces, which includes Górnicki mappings, enriched Kannan mappings, enriched Chatterjea mappings, and enriched mappings.
P. Dhivya, D. Diwakaran, P. Selvapriya
semanticscholar +1 more source
Best proximity points and fixed points for p-summing maps [PDF]
Fixed Point Theory and Applications, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Petric, Mihaela, Zlatanov, Boyan
openaire +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source