Results 101 to 110 of about 10,796 (154)

STAT1/3/5 Functions Driving Lipid and Energy Metabolism in Cancer and Immunity. [PDF]

Int J Mol Sci
Rinnerthaler M, Sykora M, Christoforakos A, Aberger F, Ferbeyre G, Moriggl R.   +5 more
europepmc   +1 more source

Catecholamines Activate a Tumour Progression Program in Differentiated Tumour Hepatocytes

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims The sympathetic nervous system is involved in the progression and aggressiveness of several cancers, including hepatocellular carcinoma (HCC). However, the specific effects of sympathetic innervation and catecholamines on tumour hepatocyte behaviour remain poorly understood.
Elise Lelou, Claudine Rauch, Hélène Dubois‐Pot‐Schneider, Marjorie Dufresne, Abolfazl Zekri Yazdi, Maelle Guillout, Luis Cano, Lise Desquilles, Nicolas Nesseler, Marc Bourgeois, Claude Bendavid, Julie Massart, Orlando Musso, Anne Corlu, Caroline Aninat   +14 more
wiley   +1 more source

Berberine ameliorates acute hyperglycemia and hypoinsulinemia induced by ketamine/xylazine in rats: role of alpha₂ adrenergic receptors, oxidative stress and inflammatory suppressing mechanisms. [PDF]

BMC Vet Res
Kadhim RA, Erfanparast A, Tamaddonfard E, Amirkashani D, Imani M.   +4 more
europepmc   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

G-protein coupled receptors synergy in bone health: new avenues for osteoporosis detection and <i>in vitro</i> modeling. [PDF]

Front Endocrinol (Lausanne)
Sopova JV, Krasnova OA, Kriukova JD, Mukhamedshina YO, Zakirova EY, Rizvanov AA, Lesnyak OM, Neganova IE.   +7 more
europepmc   +1 more source

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

The Journal of Physiology, Volume 604, Issue 15, Page 6281-6301, 1 August 2026.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba, Peter R. Levasseur, Samuel D. Newton, Khia Min Sabrina Koh, Paige C. Arneson‐Wissink, Xinxia Zhu, Peter Pham, Heike Mendez, Luke Whitcomb, Ariana Sattler, William R Woodward, Beth A. Habecker, Daniel L. Marks, Aaron J. Grossberg   +13 more
wiley   +1 more source

Cirrhotic Cardiomyopathy: Bridging Hepatic and Cardiac Pathophysiology in the Modern Era. [PDF]

J Clin Med
Lupu D, Scârneciu CC, Țînț D, Tudoran C.   +3 more
europepmc   +1 more source

CaV1.2 dynamics in native male arterial myocytes

The Journal of Physiology, Volume 604, Issue 15, Page 6302-6323, 1 August 2026.
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel, Hannah Voorhees, Arsalan U. Syed, Maryann K. Ferrara, Mary Horne, Johannes W. Hell, Luis F. Santana, Rose E. Dixon, Madeline Nieves‐Cintron, Manuel F. Navedo   +9 more
wiley   +1 more source

ß-adrenergic-like signalling engages CrebB in Drosophila gut to promote female longevity. [PDF]

Nat Commun
Sumit AF, Whitehead B, Özyeşil I, Shen D, Anver S, Foukas LC, Alic N.   +6 more
europepmc   +1 more source

The Cavβ4 subunit of Cav1.2 channels antagonizes isoproterenol‐induced hypertrophy in rat cardiac muscle cells by down‐regulating miR‐183‐5p

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract The Cavβ4 subunit of voltage‐gated Cav1.2 channels regulates gene expression in neurons and cardiac cells. It increases the expression of interferon‐β–related genes in H9c2 cardiomyocytes derived from rat ventricular tissue, but the possibility that it also regulates the expression of microRNAs (miRs) remains unexplored.
Elba D. Carrillo, Erick Galicia, María C. García, Jorge A. Sánchez   +3 more
wiley   +1 more source