Results 121 to 130 of about 10,836 (202)

Latest Advances in Obesity Treatment by Regulating Adipocyte Thermogenesis. [PDF]

PPAR Res
Nie T, Chen J, Wang Z, Mao L.
europepmc   +1 more source

Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi, Xi Liu, Xi Zhang, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Differential conservation analysis identifies residues defining constitutive internalization in beta-adrenergic receptors. [PDF]

iScience
Walker AR, Selçuk B, Erol I, Durdağı S, Hanyaloglu AC, Adebali O.   +5 more
europepmc   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, Volume 10, Issue 3, Page 269-280, June 2026.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Pharmacological interventions targeting β-adrenoceptors in colorectal cancer: an evolving paradigm. [PDF]

Inflammopharmacology
Ghosn A, Bassam K, Al Zein M, Nasser SA, Pintus G, Eid AH.   +5 more
europepmc   +1 more source

Orchestrating mitochondrial protein import: The emerging role of DYRK1A in health and disease

Protein Science, Volume 35, Issue 6, June 2026.
Abstract The translocase of the outer mitochondrial membrane (TOM complex) serves as the central entry gate for more than 1000 nuclear‐encoded precursor proteins imported into the organelle. Recently, the human import receptor TOM70 has been identified as a substrate of the serine/threonine kinase DYRK1A.
Sahana Shankar, Chris Meisinger
wiley   +1 more source

The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma. [PDF]

J Cell Mol Med
Caniceiro AB, Agostinho SP, Piochi LF, Rosário-Ferreira N, Moreira IS.   +4 more
europepmc   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan, Katie Powell, Russ Chess‐Williams, Catherine McDermott   +3 more
wiley   +1 more source

Β3-Adrenergic Receptors and Prematurity-Related Diseases: A Systematic Review. [PDF]

Children (Basel)
Fazi C, Dani C.
europepmc   +1 more source

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto, Lucia Buccarello, Giuseppe Carota, Rocco Salvatore Calabrò, Carmela Rifici, Emanuela Esposito, Alessio Ardizzone, Giuseppe Caruso   +7 more
wiley   +1 more source