Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background and Aims Xerostomia, or dry mouth, significantly impairs quality of life and oral health, particularly in patients subjected to radiation therapy or suffering from systemic disorders. This narrative review summarizes the current evidence on the efficacy and safety of gene therapy interventions for xerostomia, exploring innovative ...
Muhammad Usman Bilal +6 more
wiley +1 more source
Proteomic and Super‐Resolution Analyses of Murine Brown Adipocyte‐Derived Extracellular Vesicles
Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.Graphical Abstract ABSTRACT Thermogenic brown adipocytes (BAs) are not only an energy sink but also regulate systemic metabolic health through secreted factors and extracellular vesicles (EVs). Here, we investigate the baseline profiles BA‐EVs and how cold‐induced thermogenesis alters the proteome of BA‐EVs.
Menchus Quan +8 more
wiley +1 more source
Effect of the gut microbiota metabolite phenylacetylglycine on cardiac Ca<sup>2+</sup> signaling. [PDF]
Biophys Rep (N Y)Bovo E, Zima AV.
europepmc +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
MedComm, Volume 7, Issue 5, May 2026.Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
Targeted Therapies in Infantile Hemangiomas and Vascular Malformations: From β-Blockers to PI3K/AKT/mTOR Inhibitors. [PDF]
J Cell Mol MedArasiewicz H, Dec M.
europepmc +1 more source
Histone Modifications in Cardiovascular Disease: Mechanisms and Therapeutic Opportunities
MedComm, Volume 7, Issue 5, May 2026.This graphical abstract summarizes how classical and emerging histone posttranslational modifications (PTMs), together with their chromatin regulators (writers, erasers, and readers), govern major pathobiological programs in cardiovascular disease.
Yu Zheng +8 more
wiley +1 more source
Cross-Talk Between Signaling and Transcriptional Networks Regulating Thermogenesis-Insights into Canonical and Non-Canonical Regulatory Pathways. [PDF]
Int J Mol SciSimka-Lampa K.
europepmc +1 more source
Phytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli +4 more
wiley +1 more source
The slow delayed rectifier K<sup>+</sup> current is differently regulated under baseline conditions and following β-adrenergic stimulation in canine ventricular cardiomyocytes. [PDF]
Sci RepHorváth B +7 more
europepmc +1 more source