Results 161 to 170 of about 61,745 (283)

Neurotransmitters in tumors: chemical cross-talk shaping tumor progression. [PDF]

Biomark Res
Chen W, Yu J, Ge S, Yuan T, Ding X, Yan B, Ye L, Wang Y, Jia R.   +8 more
europepmc   +1 more source

The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance [PDF]

, 2009
Ersilia Cipolletta, Alfonso Campanile, Gaetano Santulli, Emma Sanzari, Dario Leosco, Pietro Campiglia, Bruno Trimarco, Guido Iaccarino   +7 more
openalex   +1 more source

Isoprenaline shows unique kinase dependencies in stimulating β₁AR-β-arrestin2 interaction compared to endogenous catecholamines. [PDF]

Mol Pharmacol
Matthees ESF, Kletzin LE, Löbbert A, Hoffmann JS, Große C, Gossert AD, Hoffmann C.   +6 more
europepmc   +1 more source

Immune Surveillance and Immune Escape in Cancer: Mechanisms and Immunotherapy

MedComm, Volume 6, Issue 10, October 2025.
Our review focused on how specific cellular subsets crucial for igniting tumor immunity cycle, notably effector and helper T cells alongside antigen presentation cells, interact closely in both antigen‐dependent and ‐independent manners (within centered ring) adjacent to cancer cells.
Ying Peng, Linsheng Zhan, Jianxiang Shi, Jie Wang, Yueying Li, Xiangdong Sun, Jie Lv, Huiyu Yang, Zan Qiu, Xingzhao Liu, Chenyan Li, Shanshan Gong, Wen Jia, Huiying Wang, Yuqi Zhao, Bin Zhang, Wei Guo, Jiancheng Guo, Jian Shang, Qianqian Zhou, Yanan Yang, Feng Gao   +21 more
wiley   +1 more source

Arrestins as Possible Drug Targets. [PDF]

Biomol Ther (Seoul)
Cinviz ZN, Moroni E, Sensoy O, Morra G, Gurevich VV.   +4 more
europepmc   +1 more source

G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers

MedComm, Volume 6, Issue 10, October 2025.
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan, Sana Khurshid, Saud Almawash, Rakesh Kumar, Ammira S. Al‐Shabeeb Akil, Ajaz A. Bhat, Muzafar A. Macha   +6 more
wiley   +1 more source

Specific enhancement of beta-adrenergic receptor kinase activity by defined G-protein beta and gamma subunits. [PDF]

, 1993
Sabine Müller, Mirko Hekman, Martin J. Lohse   +2 more
openalex   +1 more source

Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart.

Circulation Research, 2000
A. Eckhart, S. J. Duncan, R. Penn, J. Benovic, R. Lefkowitz, W. Koch   +5 more
semanticscholar   +1 more source

ActSeek: fast and accurate search algorithm of active sites in alphafold database. [PDF]

Bioinformatics
Castillo S, Ollila OHS.
europepmc   +1 more source

Heart Regeneration and Repair: Molecular Mechanism and Therapeutic Targets

MedComm, Volume 6, Issue 10, October 2025.
Regarding the general picture of heart regeneration therapy, it encompasses exogenous cell therapy, endogenous medications, metabolism, interventions in gene pathways, as well as the therapeutic strategies in the burgeoning interdisciplinary field of medicine and engineering in recent years.
Mingchuan Liu, Tingwei Peng, Rui Yu, Kexin Wang, Di Wang, Xiaojie Jia, Yan Zhang, Jianqiang Hu, Bingchao Qi, Yan Li   +9 more
wiley   +1 more source