The palmitoyl acyltransferase DHHC5 mediates beta-adrenergic signaling in the heart by targeting Gα proteins and G protein-coupled receptor kinase 2 [PDF]
Jessica J. Chen +3 more
openalex +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa. [PDF]
Vainionpää K, Montaser AB, Leinonen H.
europepmc +1 more source
Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management
Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu +5 more
wiley +1 more source
β<sub>2</sub>-Adrenergic Receptor Agonists in Diabetic Kidney Disease: Exploring a New Frontier. [PDF]
Hegde S +4 more
europepmc +1 more source
Abstract High‐risk neuroblastomas exhibit a high degree of intratumoral heterogeneity. Single‐cell RNA sequencing has greatly improved our understanding of these tumors, but the method lacks cellular tissue context and spatial information about local signaling dynamics.
Joachim T Siaw +10 more
wiley +1 more source
GPCR kinases phosphorylate GPCR C-terminal peptides in a hierarchical manner. [PDF]
Löbbert A +5 more
europepmc +1 more source
Emerging Nanonutraceuticals against Obesity
This overview comprehensively compiles the latest research advancements in diversiform nanonutraceuticals against obesity. These nanonutraceuticals are derived from the nanomodifications of some carbohydrates, lipids, proteins, vitamins, minerals, and phytochemicals.
Linjie Ni +8 more
wiley +1 more source
Proinflammatory transcriptomic and kinomic alterations in astrocytes derived from patients with familial Alzheimer's disease. [PDF]
Siciliano B +12 more
europepmc +1 more source
Preoperative Activation of c-Src Kinase in Atrial Tissue in Patients Developing Postoperative Atrial Fibrillation. [PDF]
Bonda TA +5 more
europepmc +1 more source

