Results 171 to 180 of about 61,745 (283)

Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu   +5 more
wiley   +1 more source

Spatial transcriptomics exploration of the primary neuroblastoma microenvironment in archived FFPE samples unveils novel paracrine interactions

open access: yesThe Journal of Pathology, Volume 267, Issue 2, Page 181-195, October 2025.
Abstract High‐risk neuroblastomas exhibit a high degree of intratumoral heterogeneity. Single‐cell RNA sequencing has greatly improved our understanding of these tumors, but the method lacks cellular tissue context and spatial information about local signaling dynamics.
Joachim T Siaw   +10 more
wiley   +1 more source

GPCR kinases phosphorylate GPCR C-terminal peptides in a hierarchical manner. [PDF]

open access: yesCommun Biol
Löbbert A   +5 more
europepmc   +1 more source

Emerging Nanonutraceuticals against Obesity

open access: yesSmall Science, Volume 5, Issue 10, October 2025.
This overview comprehensively compiles the latest research advancements in diversiform nanonutraceuticals against obesity. These nanonutraceuticals are derived from the nanomodifications of some carbohydrates, lipids, proteins, vitamins, minerals, and phytochemicals.
Linjie Ni   +8 more
wiley   +1 more source

Proinflammatory transcriptomic and kinomic alterations in astrocytes derived from patients with familial Alzheimer's disease. [PDF]

open access: yesBrain Behav Immun Health
Siciliano B   +12 more
europepmc   +1 more source

Preoperative Activation of c-Src Kinase in Atrial Tissue in Patients Developing Postoperative Atrial Fibrillation. [PDF]

open access: yesMedicina (Kaunas)
Bonda TA   +5 more
europepmc   +1 more source

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